Pancreas division

Pancreatic division (PD) is a congenital malformation characterized by an anastomosis of the main and parapancreatic ducts during the development of the pancreas that is completely unfused or only anastomosis of thin branching pancreatic ducts. Unfused ducts, abnormal pancreatic duct fusion, etc., may cause pancreatitis due to poor drainage of pancreatic juice. Asymptomatic people do not require special treatment. The occurrence of pancreas occurs in the fourth week of human embryonic development. Initially, a bud process is extended from the dorsal and ventral sides of the caudal end of the foregut, called ventral pancreas and dorsal pancreas. By week 7, the abdominal pancreas has shifted from the ventral side of the duodenum to the dorsal side, fused with the dorsal pancreas to form a complete pancreas. The abdominal pancreas forms the majority of the pancreatic head, and the dorsal pancreas forms a small part of the pancreatic head and the pancreatic body And pancreatic tail, while the dorsal and abdominal pancreas are fused, the ducts are also fused to each other. The main pancreatic duct (Wirsung duct) is formed by the fusion of the ventral duct and the dorsal duct. Opening in the main duodenum of the duodenum, most of the pancreatic juice is drained to the duodenum through the main nipple. The proximal part of the dorsal pancreatic duct gradually degenerates or even disappears. If it remains, it is called the parapancreatic duct (santorini duct). A small part of the pancreatic fluid is drained, and it opens in the duodenal parapapilla. If the embryo development stops in the state of the fetus 7 weeks ago, the dorsal and ventral pancreatic ducts fail to fuse or the anastomosis of thin pancreatic ducts is the main The pancreatic duct can only drain pancreatic juice secreted by the ventral pancreas, and the parapancreatic duct becomes pancreas The main drainage tube of the gland is responsible for the drainage of pancreatic body and tail pancreatic fluid. This abnormality is PD.

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