Aldosterone deficiency

Aldosterone deficiency, also called hypoaldosteronism, is an endocrine disease caused by reduced aldosterone (ALD) secretion or defective peripheral effects. Clinically, the main manifestations are hyperkalemia, hyponatremia, hypovolemia, orthostatic hypotension, and urine salt loss. Aldosterone deficiency may be one of the manifestations of total adrenal insufficiency, or it may be purely selective aldosterone deficiency. The former includes Addison's disease, congenital adrenal hyperplasia, chronic hypopituitarism, infection, bleeding or metastasis to destroy the adrenal gland, and surgically removed adrenal gland; the latter refers to insufficient selective secretion of aldosterone, and other adrenal hormones such as glucocorticoid ) Normal, or due to defects in peripheral effects of ALD.

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