Pheochromocytoma crisis in the elderly
Pheochromaffin cells, mainly distributed in chromaffin tissues such as adrenal medulla and sympathetic ganglia, are responsible for the synthesis, storage, and release of norepinephrine and epinephrine. A tumor originating from mature pheochromocytoma is called pheochromocytoma, and its clinical manifestations are characterized by a series of syndromes caused by excessive catecholamines (norepinephrine and epinephrine), with hypertension being the most prominent symptom. Because the tumor releases a large amount of catecholamines into the blood, it causes severe clinical symptoms such as hypertension crisis, hypotension shock, and severe arrhythmia, which is called pheochromocytoma crisis.
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