Choroidal neovascularization

Choroidal neovascularization, also called subretinal neovascularization, is a proliferative blood vessel from choroidal capillaries, which expands through the rift of Bruch membrane, between Bruch membrane and retinal pigment epithelium, or between neuroretina and retinal pigment epithelium, or located in the retina Pigment epithelium and choroid proliferate. It is more commonly found in the macula, which severely damages central vision. This disease is extremely common and has become one of the main causes of blindness. Early detection and timely treatment are of great clinical significance. As early as 1876, Sattle noticed in the histological examination of the normal adult eye that half of the people had new blood vessels between the periphery of the retina and the Bruch membrane. Reichling et al. Have confirmed that such capillary networks often appear in the periphery of the fundus. Friedman et al. Used enzymatic digestion technology and found that new blood vessels appeared between the Bruch's membrane and retinal pigment epithelium in the serrated marginal region, which is common in adult eyes, and especially common in people over 60 years of age.

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