Inclusion body myositis and hereditary inclusion body myopathy

Inclusion body myositis (IBM) is a chronic inflammatory myopathy. The main pathological feature is the inclusion of tubular filaments in the muscle or nucleus. Yunis first used this name in 1971. In 1978 Carpenter summarized the clinicopathological characteristics of 14 cases of IBM, and formally established IBM as an independent disease. In 1995, Griggs and others published a feature article, which proposed IBM's clinical and laboratory diagnostic standards, and further confirmed IBM's clinical pathology concepts. In 1993, Askanas et al described hereditary inclusion body myopathy (hereditary inclusion body myopathy (h-IBM) as a hereditary inclusion body myopathy (h-IBM ). Because inclusion body myositis is mostly sporadic, it is customary to call sporadic inclusion body myositis (s-IBM) to distinguish it from h-IBM.

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