Empty saddle syndrome

Empty sella syndrome refers to a group of syndromes caused by subarachnoid hernia into the pituitary fossa, which deforms the pituitary gland under compression and enlarges the saddle. The term empty saddle syndrome was first used in 1949 by Sheehan and Summers to describe postpartum pituitary necrosis. In the past, some people also call it saddle defect, intraarachnoid cyst or diverticulum. By 1950, Busch had investigated autopsy data of 788 cases of known pituitary diseases, and found that 40 cases of saddles were absent, and the saddle was filled with the subarachnoid space. So far, empty saddle syndrome has generally been regarded as an independent disease.

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