Macroglobulinemia
The abnormal increase of IgM in the blood is macroglobulinemia. The disease is divided into primary and secondary. The etiology of primary macroglobulinemia is unknown, also known as Fahrenheit macroglobulinemia. This disease is divided into primary and secondary, and the increase of unexplained monoclonal lgM is called primary macroglobulinemia (Waldenstrom macroglobulinemia). Monoclonal or polyclonal lgM secondary to other diseases The increase is called secondary macroglobulinemia. The clinical manifestations of primary macroglobulinemia are characterized by aging, anemia, bleeding tendency, and hyperviscosity syndrome. The diagnosis was based on the presence of a large amount of monoclonal lgM in the blood and lymphoid plasma cell infiltration in the bone marrow. The disease is a chronic process. Chemotherapy should not be used when there are no clinical symptoms. Chemotherapy is used for progressive diseases.
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