Paroxysmal nocturnal hemoglobinuria in children

Paroxysmal noctuRNAl hemoglobinuria (PNH) is a chronic hemolytic disease with acquired acquired hematopoietic stem cell gene mutation that causes red blood cell membrane disease. In clinical, intermittent intravascular hemolysis, hemoglobinuria, sleep Features of increased hemolysis. Both men and women can develop the disease, with more men. More common in young adults, rare in childhood. Also known as paroxysmal nocturnal hemoglobinuria, Marie-Michel syndrome, paroxysmal nocturnal hemoglobinuria, and paroxysmal nocturnal hemoglobinuria.

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