Refractory epilepsy

Intractable epilepsy is also called refractable epilepsy, and there is no unified definition at home and abroad. Usually refers to no central nervous system disease or occupying lesions, but clinical delay, after more than 2 years of regular antiepileptic treatment, trial of major antiepileptic drugs alone or in combination, to achieve the maximum tolerated dose for patients, blood concentration reached effective Range, still unable to control the seizures, and affect daily life before it can be determined as refractory epilepsy. Refractory epilepsy accounts for about 20% to 30% of patients with epilepsy.

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