Infectious monocytes

Infectious mononucleosis is an acute proliferative disease of the mononuclear-macrophage system, and the course is often self-limiting. Clinical manifestations include irregular fever, lymphadenopathy, sore throat, and significant increase in peripheral blood mononuclear cells, abnormal lymphocytes, heterophilic agglutination tests, and anti-EB virus antibodies in serum. Approximately half of the primary infections of EB virus in young and adult patients are infectious mononucleosis. Burkittis lymphoma in African children (BL and nasopharyngeal carcinoma only occur in patients who have been infected with EB virus, and the tumor cells of BL and nasopharyngeal carcinoma carry EB virus DNA and virus-determined nuclear antigens, so it is believed that EB virus may be an important pathogenic factor for BL and nasopharyngeal carcinoma.

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