Fungal allergic asthma

Clinical knowledge of fungal allergic asthma has been around for more than 200 years. In 1728, John Floyer reported that someone had a sudden onset of asthma while visiting a winery. In 1924 Von Leeuwen suggested that the cause of asthma in the Netherlands was due to humidity. In the United States in the same year, Cadhan reported three cases of asthma induced by wheat rust, and these findings are the embryonic form of fungal allergic asthma. In 1928, Dr. Hansen of Germany officially confirmed for the first time that 15% of asthma patients had positive skin tests of Alternaria and Penicillium antigens collected in their living environment, and confirmed that inhalation of Alternaria or Penicillium to some of them Mold spores can induce asthma attacks. In 1932, Tubs reported that a child with asthma became ill after each meal of fermented food, and suggested that yeast and Candida were the cause of the disease in some patients with asthma. In 1934, Prince and others used a method of culturing fungi in a patient's living environment to observe the fungus. It was found that when the fungus grows vigorously, the patient's asthma symptoms worsen.

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