Anti-GBM antibody

Pulmonary hemorrhage-nephritis syndrome, also known as anti-basal membrane glomerulonephritis, Goodpasture syndrome or Goodpasture disease, may be caused by viral infection and / or inhalation of certain chemicals. It is a severe damage to the glomerulus and alveolar wall basement membrane caused by anti-basement membrane antibodies. The clinical manifestations are pulmonary hemorrhage, aggressive glomerulonephritis and serum anti-glomerular basement membrane (GBM) antibody positive triad. Most patients progress rapidly and have a dangerous prognosis.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.