Glomerular basement membrane moth phagocytosis

The glomerular basement membrane moth phagocytosis is one of the diagnostic basis of nail-patella syndrome. Renal biopsy specimens cannot be judged only by the glomerular basement membrane moth phagocytosis phenomenon. Phosphotungstic acid staining must be used to identify fibrils because of their higher sensitivity and more valuable diagnosis. Nail-patella syndrome is a hereditary disease whose mode of transmission is autosomal dominant. The incidence rate is 4.5 / 1 million to 22/1 million, and there is no gender difference. Patients have a 50% chance of passing on to their offspring, with the genetic locus linked to the adenylate cyclase and ABO blood type loci on chromosome 9. Looij et al. Inferred from their own data and information that if a patient of this syndrome family has obvious clinical renal manifestations, the risk of developing children with kidney disease is 1/4 and the probability of developing renal failure is 1 / 10.

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