Gradually become stupid

Gradually stupid appearance refers to the rough and stupid changes of the patient's appearance due to bone lesions during development. The appearance of gradually becoming stupid is one of the typical manifestations of mucopolysaccharidosis type Ⅰ. It is a group of hereditary mucopolysaccharide metabolism disorders caused by lysosomal abnormalities. The common clinical feature of congenital rheumatism caused by the incomplete decomposition of glucosamine accumulation due to the deficiency of enzyme activity is the varying degree of epiphysis. , Mental retardation, visceral involvement and corneal turbidity; biochemical characteristics are acidic mucopolysaccharide catabolism defects that cause excessive accumulation of mucopolysaccharides in the cells and excessive mucopolysaccharides in urine.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.