Poor R wave increase in transition zone

Poor R wave progression in the transition zone: Coronary arteries can be caused by amyloidosis. About 80% of patients have pathological Q waves or poorly increasing R waves in the transition zone. Amyloid cardiomyopathy is a myocardial disease caused by the deposition and infiltration of amyloid in the heart. The pathogenesis of amyloid cardiomyopathy (cardiacamyloidosis) is unknown, but it is currently considered to be a protein conformation disease. Misfolding of extracellular proteins plays an important role, leading to insoluble and toxic proteins in the beta sheet fibers of tissue Protein deposition, which is related to immune, genetic, inflammation and other factors. Myocardial amyloidosis may be related to an aspartate-18glutamate mutation of thyroxin.

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