Atrophy of interosseous and intermuscular muscles
It usually starts with small hand muscle weakness and gradual muscle atrophy, which can spread to one or both sides, or to the opposite side after starting from one side. Due to the atrophy of the big and small fish muscles, the palms are flat, and the interosseous muscles are atrophied to form claw-shaped hands. Muscle atrophy extends upwards, gradually invading the forearm, upper arm, and shoulder straps. Myofibrillation is common and can be confined to certain muscle groups or widely present. It can be easily induced by patting with your hands. A small number of muscle atrophy can start from the tibialis anterior and fibula muscles of the lower limbs or from the extensors of the neck, and in some cases the proximal muscles of the upper and lower limbs.
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