Hypergastrinemia

Gastrin is an important gastrointestinal hormone that is mainly secreted by G cells. G cells are typical open cells, with the gastric antrum most, followed by the fundus, duodenum, and jejunum. D cells of human islets can also secrete gastrin. Hypergastrinemia, which is divided into two types of hypergastric acid hypergastrinemia and hypogastric acid or non-acid hypergastrinemia. In patients with gastrinoma, serum gastrin levels are high, and they are often accompanied by hyperplasia and hypertrophy of the gastric mucosa.

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