RPR

The rapid plasma reagin test is an improvement of the VDRL antigen. The sensitivity and specificity are similar to VDRL. The advantage is that the results can be read with the naked eye. Cardiolipin is used as an antigen to measure anticardiolipin antibodies in serum, also known as reactin. This test has high sensitivity and low specificity, and is prone to biological false positives. After adequate treatment of patients with early syphilis, reptin can disappear, and those who have not been treated early to late can also reduce or disappear in some patients. Currently it is generally used as a screening and quantitative test to observe efficacy, recurrence and reinfection.

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