Effusion lactate dehydrogenase
Lactate dehydrogenase is a glycolytic enzyme. Lactate dehydrogenase exists in the cytoplasm of all tissue cells in the body, with kidney content being higher. Lactate dehydrogenase is an enzyme that catalyzes the dehydrogenation of lactic acid to pyruvate and is found in almost all tissues. There are five isozymes, namely LDH-1 (H4), LDH-2 (H3M), LDH-3 (H2M2), LDH-4 (HM3) and LDH-5 (M4), which can be separated by electrophoresis . The distribution of LDH isoenzymes has obvious tissue specificity, so it can be used to diagnose diseases based on its tissue specificity. Normal human serum LDH2,> LDH1. If myocardial enzymes are released into the blood then LDH1> LDH2, and this indicator can be used to observe and diagnose myocardial diseases. LDH is found in almost all tissues. The human body has the highest kidney consumption, and the myocardium, skeletal muscle, liver, and red blood cells decrease in order. Lactate dehydrogenase in effusion is more diagnostic.
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