Deepening of frontal striations

Introduction The increase in the amount of transverse stripes is a symptom of thick-skinned periostosis. Pachyermoperiostosis is also known as cutaneous hypertrophic periosteal hyperosteogeny and Touraine-Solente-Gole syndrome. The primary may be autosomal dominant. Secondary is also called hyperproliferative osteoarthrosis. Often secondary to a variety of chronic and malignant neoplastic diseases. The pathogenesis is still unclear. Primary: more common in men, often soon after puberty. Secondary: After the middle age, the disease is more common in women, the skin can not change, and the amount of horizontal stripes is deepened. It can be diagnosed based on typical changes in skin and bone.

Cause

(1) Causes of the disease

The primary may be autosomal dominant. Secondary is also called hyperproliferative osteoarthrosis. Often secondary to a variety of chronic and malignant neoplastic diseases. The primary manifestations of this disease are more common in men after secondary middle-aged disease, and there are no other relevant descriptions in women.

(two) pathogenesis

The pathogenesis is still unclear.

an examination

Related inspection

Tumor-associated antigen mammography

First, physical examination

The face, forehead, and head are thick and wrinkled, and the forehead changes particularly prominently. The head is turned back to the cranium, especially the upper eyelids are thick and slack, the ears and lips are also thick, especially large, and the skin of the hands and feet is also thick. The bones of the extremities and the phalanx are hypertrophied, the fingers and toes are sick, and the sacs and knee joints are effusion. The patient has pain in his limbs and his movements are awkward.

Second, laboratory inspection

X-ray examination showed proliferative periostitis such as humerus, humerus, humerus and ulna, and diffuse periosteal thickening.

Differential diagnosis

It should be differentiated from the cause of female symptoms with increasing age.

The disease has two types, primary and secondary.

Primary

More common in men, often onset shortly after puberty. The face, forehead, and head are thick and wrinkled, and the forehead changes particularly prominently. The head is turned back to the cranium, especially the upper eyelids are thick and slack, the ears and lips are also thick, especially large, and the skin of the hands and feet is also thick. The bones of the extremities and the phalanx are hypertrophied, the fingers and toes are sick, and the sacs and knee joints are effusion. The patient has pain in his limbs and his movements are awkward.

2. Secondary

After middle-aged disease, the incidence of women is more common, the skin changes are not significant, the bone lesions are obvious and fast, and the pain is conscious. After the primary disease is alleviated, the bone and skin lesions are alleviated.

According to the typical changes of skin and bone can be diagnosed, X-ray examination of the tibia, tibia, tibia, ulna and other proliferative periostitis, diffuse periosteal thickening.

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