Nails that are tarnished and flat become thin and brittle with white streaks

Introduction The nails lose their luster and are in a state of thinness and brittleness. White streaks are common in arsenic poisoning. Arsenic has affinity with hair and nail keratinized tissues. Whether it is chronic arsenic poisoning or acute arsenic poisoning, it is still alive after poisoning. More than one week, more arsenic can be found in the hair. Arsenic poisoning, often called arsenic poisoning, mostly due to misuse or excessive toxic poisoning. Inhalation of powder, smoke or contaminated skin poisoning during production and processing is also common. The disease is focused on prevention and avoids direct exposure to arsenic.

Cause

Arsenic poisoning is generally caused by the excessive dose of arsenic-containing drugs. It can also be poisoned by eating arsenic-containing poisonous rats, snails, insecticides, and fruits and vegetables that have just been sprayed by such insecticides. Poultry, livestock and so on.

Arsenic trioxide (also known as arsenic, red, white stone, etc.) is commonly used in the rural areas of northern China to kill seedlings and kill pests. It is very toxic, and its pure appearance is similar to salt, sugar, flour, gypsum, etc. Misuse caused poisoning. There are also people who have been poisoned by well water and food contaminated with arsenic trioxide. Mother poisoning can cause fetal and milk poisoning. In recent years, it has been reported that the case of chronic arsenic poisoning caused by taking Niuhuang Jiedu Tablet has to be paid attention to because the Niuhuang Jiedu Tablet contains realgar (the main component is arsenic trisulfide).

an examination

Related inspection

Trace element detection in blood routine human body

Oral acute arsenic poisoning early common gastrointestinal symptoms, such as dry mouth, pain, burning, tightness in the mouth and throat, hoarseness, nausea, vomiting, difficulty in swallowing, abdominal pain and diarrhea. The vomit is firstly the contents of the stomach and the water of the rice bran, followed by blood, mucus and bile, sometimes mixed with small pieces of unabsorbed arsenic; the vomit may have a garlic-like odor. Severe cases are very similar to cholera, and began to discharge a large amount of watery stools, which later became bloody, or mixed with bloodshots of rice bran water samples, and soon dehydration, acidosis and even shock. At the same time, there may be headache, dizziness, irritability, convulsions, toxic myocarditis, and polyneuritis.

A few have nasal and skin bleeding. Severely ill children may experience respiratory, circulatory, liver, kidney and other functional failures and central neuropathy from 24 hours to several days after poisoning. Dangerous signs such as dyspnea, convulsions and coma may occur. A small number of patients may be 20 minutes to 48 hours after poisoning. There is shock and even death, and the symptoms of the gastrointestinal tract are not significant. The sick child may have an attack of hematoporphyria, and the urinary fistula is strongly positive.

Hydrogen sulfide poisoning often has hemolysis. Symptomatic symptoms of multiple neuritis during subacute poisoning, abnormal limbs, first pain, numbness, then weakness, weakness, until complete paralysis or incomplete paralysis, the appearance of wrist sag, foot and sacral reflex disappeared; or have difficulty swallowing , pronunciation and breathing disorders. Skin flushing or erythema sometimes occurs due to vasomotor dysfunction.

Patients with chronic poisoning often show weakness, loss of appetite, occasional nausea, vomiting, constipation or diarrhea. Leukocyte and thrombocytopenia, anemia, red blood cell and bone marrow cell formation disorders, hair loss, stomatitis, rhinitis, nasal septum ulcers, perforation, skin pigmentation, and exfoliative dermatitis may occur. The palm and toe skin is hyperkeratotic, the nails lose their luster and are in a state of being flat, brittle, white stripes appear, and liver and myocardial damage. The arsenic, urinary arsenic and finger arsenic levels of the poisoned patients increased. Children who take a large amount of arsenic orally can find substances that cannot be penetrated by X-rays in the gastrointestinal tract when they are examined by abdominal X-ray.

Differential diagnosis

Arsenic poisoning is easily confused with the following diseases:

Chronic mild poisoning

1. The skin is hyperkeratotic, especially in the palmar area.

2. There are diffuse black or tan pigmentation and pigmentation spots on the trunk and limbs.

3. Mild liver damage.

4. Mild peripheral neuropathy.

Chronic severe poisoning, on the basis of chronic mild poisoning, has one of the following manifestations:

1. Cirrhosis of the liver.

2, peripheral neuropathy with limb dyskinesia or limb paralysis.

3, skin cancer.

Oral acute arsenic poisoning early common gastrointestinal symptoms, such as dry mouth, pain, burning, tightness in the mouth and throat, hoarseness, nausea, vomiting, difficulty in swallowing, abdominal pain and diarrhea.

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