Intrapancreatic calcification

Introduction Pancreatic calcification refers to a bit of high-density tissue in the pancreas. Chronic pancreatitis refers to the pathological process of atrophy of pancreatic islets and islet tissue and extensive fibrosis of the pancreas. Often accompanied by calcification and pseudocyst formation. Clinically, it is mainly characterized by abdominal pain, diarrhea or steatorrhea, weight loss and malnutrition such as pancreatic insufficiency. CT intracranial calcification confirmed the presence of pancreatic stones. More common in alcoholic or familial pancreatitis, acute pancreatitis can form extensive calcification in pancreatic tissue.

Cause

The cause of calcification in the pancreas:

Pancreatic calcification is the final outcome of inflammatory injury of pancreatic tissue. It is more common in alcoholic or familial pancreatitis. Acute pancreatitis can form extensive calcification in pancreatic tissue. Calcification of recurrent chronic pancreatitis can be increased with the number of episodes. Total pancreatic calcification, the mechanism of pancreatic calcification is not fully understood, and may be related to hypercalcemia.

an examination

Related inspection

MRI of liver, gallbladder, pancreas and spleen CT examination of pancreas CT examination of pancreas palpation pancreatic disease Ultrasound diagnosis of pancreatic exocrine function

Examination and diagnosis of intra-pancreatic calcification:

(A), the secretin test with pancreatic hormone to stimulate the pancreas, observe the secretion of pancreatic juice, sodium bicarbonate and trypsin.

(2) When Lundh tests this fee, it is complicated and is gradually used less.

(C), trypsin test When the pancreatic exocrine function is reduced, chymotrypsin secretion is insufficient, can cause a decrease in urine PABA content, about 60% of the normal amount. This method is simple and easy to use, and has recently been used more.

Differential diagnosis

Symptoms of calcification in the pancreas:

Islet cell destruction: Diabetes mellitus is a metabolic disorder caused by a decrease in the biological effect of insulin deficiency and (and) insulin. It is a common disease characterized by persistent elevated blood glucose and the presence of diabetes. The incidence rate is 1%. ~2%. Diabetes refers to primary diabetes, which can be divided into insulin-dependent diabetes mellitus (type I diabetes) and non-insulin-dependent diabetes mellitus (type II diabetes) according to its etiology, pathogenesis, pathology, clinical manifestations and prognosis. ).

Pancreatic fibrosis: Chronic pancreatitis is a persistent, permanent damage to pancreatic tissue and function due to various factors. Different degrees of acinar atrophy, pancreatic duct deformation, fibrosis and calcification in the pancreas, and varying degrees of pancreatic exocrine and endocrine dysfunction, clinical manifestations of abdominal pain, diarrhea or steatorrhea, weight loss and malnutrition and other pancreatic insufficiency Symptoms.

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