Inflammatory damage

Introduction Inflammatory damage refers to various factors that cause inflammation in the body and cause inflammatory damage to the tissue. Including acute and chronic synovitis, joint capsule inflammation, may be associated with temporomandibular joint disc displacement, osteoarthrosis and arthritis. More common in inflammatory reactions, inflammation is the basic pathological process of a variety of diseases, such as various infectious diseases, allergic diseases, autoimmune diseases, etc. are all inflammatory diseases. The inflammatory response is also involved in processes such as wound repair, ischemia-reperfusion injury, and multiple organ dysfunction.

Cause

Causes of inflammatory damage

More common in inflammatory reactions, inflammation is the basic pathological process of a variety of diseases, such as various infectious diseases, allergic diseases, autoimmune diseases, etc. are all inflammatory diseases. The inflammatory response is also involved in processes such as wound repair, ischemia-reperfusion injury, and multiple organ dysfunction.

The ultimate goal of the inflammatory response is to limit, clear pathogenic factors, absorb and remove necrotic tissue, repair tissue defects, and restore organ function. Therefore, the essence of inflammation is a defensive reaction of the body.

an examination

Related inspection

Blood routine blood test CT examination of serum amyloid A

Examination of inflammatory damage

First, the reaction of inflammation

Local features of inflammation are redness, swelling, heat, pain, and dysfunction. Systemic reactions caused by inflammation include fever and increased peripheral white blood cell counts. Fever is associated with infectious inflammation, especially when the pathogen spreads into the blood. Inflammation such as certain viral diseases and typhoid fever can also result in a decrease in peripheral white blood cell counts.

Second, the clinical manifestations of local inflammation

1. Red: caused by congestion.

2. Swelling: caused by exudation, especially inflammatory edema.

3. Heat: caused by hyperemia and metabolism, interleukin-1, tumor necrosis factor and prostaglandin E produced by leukocytes can cause fever.

4. Pain: Ions, inflammatory mediators, exudates stimulate the compression of nerve endings.

5. Dysfunction: parenchymal cell metaplasia, abnormal metabolism, mechanical obstruction and oppression pain.

Differential diagnosis

diagnosis:

1. Fever: Exogenous pyrogens, cytotoxins, viruses, parasites, etc. can cause fever. The endogenous pyrogen prostaglandin E, the low level of white blood cells, etc., can cause the skin to shrink, causing the body to reduce heat dissipation and cause fever.

2. Leukocytosis: A manifestation of the body's defense function, but when the typhoid bacillus is infected, the number of white blood cells in the blood is reduced.

3. Mononuclear macrophage system hyperplasia: mainly manifested as swelling, spleen and local lymphadenopathy.

4. Substantial organ lesions: When the inflammation is severe, the parenchymal cells of the heart, liver, kidney and other organs may undergo different degrees of degeneration, necrosis and dysfunction.

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