Increased blood viscosity

Introduction Blood viscosity is one of the factors that determine blood flow resistance. The viscosity of whole blood is 4-5 times that of water. Blood viscosity is an abbreviation for blood viscosity and is one of the indicators reflecting blood viscosity. The main factors affecting blood viscosity are: red blood cell aggregation and deformability, hematocrit, size and morphology, blood cholesterol, triglyceride and fibrinogen content. The body surface temperature of the human body is lower than the deep temperature, so the viscosity of the blood flows through the body surface portion. If the finger is immersed in ice water, the local blood stain can be increased by a factor of two.

Cause

Causes of increased blood viscosity

The level of blood viscosity depends on several factors:

1. Hematocrit Generally speaking, hematocrit is the most important factor determining blood viscosity. The heavier the hematocrit, the higher the blood viscosity.

2. Shear rate of blood flow: In the case of laminar flow, the ratio of the difference in blood flow velocity between adjacent layers and the thickness of the liquid layer is called the shear rate. The viscosity of a homogeneous liquid does not change with the change in shear rate, called Newtonian solution. Plasma belongs to Newtonian fluid. The viscosity of the non-homogeneous liquid increases as the shear rate decreases, and is called a non-Newtonian solution. Whole blood is a non-Newtonian solution. When blood flows in a laminar flow in the blood vessel, the red blood cells tend to move toward the central axis portion. This phenomenon is called axial flow. When the cutting rate is high, the axial flow phenomenon is more obvious. The red blood cells are concentrated in the central axis, and the long axis is parallel to the longitudinal axis of the blood vessel. The rotation of the red blood cells and the impact of the red blood cells are small, so the blood is sticky. The degree is low. When the rate of cut is low, red blood cells can aggregate and increase blood viscosity.

3. Vascular caliber: When the blood flows in a thick blood vessel, the blood vessel diameter does not affect the blood viscosity. However, when the blood flows in the arteriole having a diameter of less than 0.2 to 0.3 mm, as long as the cutting rate is sufficiently high, the blood viscosity is also lowered as the diameter of the blood vessel is further reduced. The cause of this phenomenon is not fully understood, but it has obvious benefits to the body. If there is no such reaction, the resistance of blood flowing in small blood vessels will be greatly increased.

4. Temperature: The viscosity of the blood increases as the temperature decreases. The body surface temperature of the human body is lower than the deep temperature, so the viscosity of the blood flows through the body surface portion. If the finger is immersed in ice water, the local blood stain can be increased by a factor of two.

an examination

Related inspection

Blood routine blood test

Blood viscosity increase check

It can be seen in hyperviscosity, which is a pathological syndrome characterized by increased blood viscosity. The blood flow resistance is increased and the flow is slowed down, especially for small arteries and capillaries and microcirculation, resulting in a decrease in blood perfusion. , the symptoms of ischemia and hypoxia. Such as headache, dizziness, strong neck, tinnitus, visual disturbances, numbness of the limbs, swelling, and then may cause dysfunction of the heart, brain, kidney and other organs.

Early main performance:

1 morning dizziness, awake at night.

2 Difficult after lunch.

3 squatting and working short.

4 paroxysmal vision blurred.

When the body is tested for blood, the tip of the needle is often blocked and the blood is quickly aggregated in the needle tube. When the blood rheology is measured, the blood viscosity is "+++" or more, and other indexes are also significantly increased.

Differential diagnosis

Differential diagnosis of symptoms with increased blood viscosity and confusion

Hemorheology is the science of studying blood flow and degeneration in blood vessels. Blood viscosity is an important indicator of research. The viscosity of plasma is caused by the lipids (such as cholesterol, triglycerides, lipoproteins) and a large number of The amount of molecular lipoproteins (such as fibrin, albumin, globulin) is determined. Blood lipids are one of the factors that make up the viscosity of blood. However, blood viscosity is mainly related to the number, size, aggregation, deformability of red blood cells, and the content of fibrinogen, lipids, globulin, and white eggs in plasma. Therefore, patients with hyperlipidemia can cause an increase in plasma viscosity due to an increase in serum cholesterol, triglyceride, and low-density lipoprotein levels. Increased blood viscosity slows or stagnates blood flow, reduces blood flow, causes microcirculatory disturbances, ischemia, hypoxia, nutritional disorders, and damage to organs. An increase in plasma cholesterol can lead to a decrease in red blood cell degeneration and an increase in aggregation, thereby increasing the viscosity of whole blood. An increase in the number of red blood cells in the blood is also a major cause of increased blood viscosity.

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