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Thrombotic vegetations

Introduction
Cause
Examine
Diagnosis

Introduction

Introduction A neoplasm is a general term for various protrusions formed in the pathological process inside and outside the body or organ. Thrombotic neoplasms are more common in non-bacterial thrombotic endocarditis. Non-bacterial thrombotic endocarditis can involve any heart valve, primarily affecting the mitral and aortic valves. Second, the mitral mites are mostly located in the atrial surface, and the aortic and pulmonary valves are mostly located on the ventricular surface. The main pathological change of non-bacterial thrombotic endocarditis is the formation of aseptic neoplasms on the valve. The early changes are the degeneration of valvular collagen under the influence of allergies, vitamin deficiency, hemodynamic damage and aging. The matrix edema, followed by partial exfoliation of the intima of the valve, exposes the collagen and the matrix to the bloodstream. When the antibody is in a hypercoagulable state, platelets and the like easily adhere to the surface to form non-bacterial thrombotic neoplasms. The lesions are more superficial, and there is often no inflammatory reaction in the local area. Once the neoplasms fall off, the signs of arterial embolism can be generated.

Cause

Cause

The cause of thrombotic neoplasms

The neoplasm is mostly limited to the valve. Although mostly at the junction, but does not cause valve malformation, the left atrioventricular valve is most often involved, the aortic valve is second, and again the combined valve disease. Early valvular collagen degeneration and matrix edema, followed by local exfoliation, exposure of collagen and matrix to the bloodstream, the hypercoagulable state of some tumors promotes the formation of thrombotic neoplasms, easily lead to venous thrombosis, arterial embolism Wait, cause brain, kidney, spleen or cardiac blood vessels to embolize and die.

Examine

an examination

Related inspection

Doppler echocardiography electrocardiogram partial thromboplastin time-activated partial thromboplastin time (APTT) Rerth test

Examination of thrombotic neoplasms

Diseases in which non-bacterial thrombotic endocarditis can occur are known.

The heart has a murmur or a new murmur or a change in the original murmur.

There are multiple embolisms in the body. In addition, venous thrombosis, DIC laboratory diagnosis, and multiple blood culture negatives contribute to the diagnosis of non-bacterial thrombotic endocarditis. If you find a neoplasm with UCG, it is more conducive to diagnosis.

Diagnosis

Differential diagnosis

Symptoms of thrombotic neoplasms

The disease should be differentiated from acute infective endocarditis, subacute infective endocarditis, Loffer endocarditis, Libman-Sacks endocarditis and other diseases.