Increased permeability of the gastrointestinal mucosa

Introduction Increased permeability of gastrointestinal mucosa: more common in gastric cancer and colon cancer due to necrosis of cancer tissue caused by increased permeability of the corresponding gastrointestinal mucosa, a large amount of plasma protein leaked from the gastrointestinal tract.

Cause

The cause of increased permeability of the gastrointestinal mucosa is mostly caused by gastric cancer and colon cancer.

an examination

Related inspection

Gastrointestinal gastrointestinal dysfunction dynamics examination of gastrointestinal imaging

Diagnosis of increased permeability of the gastrointestinal mucosa: A protein-deprived gastrointestinal disorder can be confirmed by a radionuclide-labeled macromolecular substance digestive tract excretion test, or an 1-antitrypsin test.

Differential diagnosis

Differential diagnosis of increased permeability of the gastrointestinal mucosa:

First, protein loss gastrointestinal disease

More common in gastric cancer and colon cancer, due to the necrosis of cancer tissue, the permeability of the corresponding gastrointestinal mucosa is increased, and a large amount of plasma protein is lost from the gastrointestinal tract. Carcinoma compresses and blocks lymphatic vessels, causing obstruction of gastrointestinal lymphatic drainage, lymphatic deposition, rupture, and loss of large amounts of protein. Clinically, hypoproteinemia and edema are the main manifestations.

Second, small intestine villi atrophy

Can be seen in colon cancer, rectal cancer, mainly manifested as diarrhea.

Third, diarrhea, dehydration and shock

Mainly found in colonic villus adenomas, occasionally in the digestive tract APUD system tumors, such as VIP tumors, gastrinoma and pancreatic polypeptide tumors. It is characterized by secretory diarrhea, which can lead to loss of water, electrolyte imbalance, and even shock.

A protein-deprived gastrointestinal disorder can be confirmed by a radionuclide-labeled macromolecular substance digestive tract excretion test, or an 1-antitrypsin test.

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