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Malabsorption of vitamin B12

Introduction
Cause
Examine
Diagnosis

Introduction

Introduction Absorption of vitamin B12: due to various factors, vitamin B12 malabsorption, resulting in the lack of vitamin B12 symptoms. If you have symptoms such as loss of appetite, indigestion, inflammation of the tongue, loss of taste, etc., it is a warning of vitamin B 12 deficiency. Pay attention to intestinal adjustment when malabsorption, the main cause of vitamin deficiency caused by gastrointestinal imbalance, should pay attention to see if there is diarrhea, gastrointestinal dysfunction and abnormal digestion, the structure of diet is unreasonable is very important reason, there are many cellulose and fruits Relationship.

Cause

Cause

With the delay of nuclear fission and the increase in the amount of synthesis, the formation of large cell bodies, nucleoplasm development is not synchronized, nuclear chromatin is loose, and the so-called "old pulp nucleus" changes the giant blood cells. The giant change is the most prominent and characteristic of the young red blood cell series, called the giant red blood cell series. Giant changes in cell morphology are also found in granulocytes, megakaryocyte lines, and even certain proliferating somatic cells. The megaloblasts are easily destroyed in the bone marrow, and ineffective erythropoiesis occurs. Eventually, the number of red blood cells is insufficient, showing symptoms of anemia. Poor diet or gastrointestinal diseases.

Examine

an examination

Related inspection

Trace elements in the human body test blood routine vitamin B1 vitamin B12 plasma vitamin B12

1. Pernicious anemia (red blood cells are insufficient).

2. Menstruation is not smooth.

3. The eyes and skin are yellow, and the skin appears local (small) redness (no pain or itching) accompanied by molting.

4. Nausea, loss of appetite, weight loss.

5. The lips, tongue and gums are white and the gums are bleeding.

6. Headache, memory loss, dementia.

7. May cause mental depression.

8. Cause nucleated giant red cell anemia (malignant anemia).

9. Spinal degeneration, neurological and peripheral nerve degeneration.

10. The mucous membranes of the tongue, mouth and digestive tract are inflamed.

11. The early manifestation of vitamin B12 deficiency in children is characterized by abnormal mental mood, sluggish expression, less crying, slow reaction, and sleep, and eventually cause anemia.

Diagnosis

Differential diagnosis

Different from the causes of anemia caused by other causes, although nutritional deficiency of folic acid, vitamin B12 is the most common cause, but should be identified with other causes of anemia, such as iron deficiency, hemorrhage, hemolysis, hematopoietic dysfunction, etc. .