Macrocephaly

Introduction The macrocephaly is caused by the thickening of the congenital cerebral cortex and the proliferation of glial cells. The brain is abnormally enlarged. It can be 1500 g (normal 390 g) at birth, or rapidly increase after birth. Larger, closed due to delay. In general, the intracranial pressure does not increase, and the cranial sac and the face increase uniformly. Although the head is large, there is no hydrocephalus, and there is no "falling sign" in the eye. The physical and mental development of the sick child can have different degrees of obstacles. There are also vision and hearing impairments, and about half of the patients have convulsions.

Cause

Congenital cerebral cortical thickening and proliferation of glial cells, abnormal brain enlargement, 1500 grams (normal 390 grams) at birth, or rapidly increase after birth. The front squat is often large and the closure is delayed. The intracranial pressure does not increase, and the cranial sac and the face increase uniformly. Although the head is large, there is no hydrocephalus, and there is no "falling sign" in the eye. The physical and mental development of the sick child can have different degrees of obstacles.

an examination

Related inspection

Brain CT examination EEG examination

The intracranial pressure does not increase, and the cranial sac and the face increase uniformly. Although the head is large, there is no hydrocephalus, and there is no "falling sign" in the eye. The physical and mental development of the sick child can have different degrees of obstacles. There are also vision and hearing impairments, and about half of the patients have convulsions. Gas brain angiography can be distinguished from hydrocephalus and brain tumors. The ventricle of this disease does not expand. The prognosis of this disease is parallel to the degree of abnormal brain development.

Differential diagnosis

Congenital hydrocephalus, hydrocephalus is mainly caused by a large increase in hydrocephalus in the brain. The clinical manifestations are mainly the rapid increase of the skull, the cranial suture is separated, the cardia is enlarged, and the head light transmission test is positive. According to the length of the disease, there are different degrees. Mental retardation and other signs of the nervous system.

Cranial stenosis: due to premature closure of the skull suture, can be divided into hereditary diseases, can also spread the disease, clinical manifestations of small cranial circumference, the formation of cerebral deformity, often with increased intracranial pressure and mental retardation.

Brain penetrating malformation: The lesion is one or more leaky head-like cavities in the cerebral hemisphere, which can communicate with the ventricle or the subarachnoid space. The symptoms are obvious mental retardation and other symptoms of the nervous system.

Microcephaly: Primary idiopathic recessive inheritance, secondary infection due to maternal viral infection or other causes, the former is often accompanied by severe mental retardation, the latter's intelligence level depends on the cause and head size And set.

Cerebral gyrus deformities, including no brain gyrus, large or small cerebral gyrus, have obvious intellectual and emotional disorders.

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