Lactose intolerance
Introduction
Introduction When the lactose that has not been decomposed and absorbed enters the colon, the bacteria present in the intestine are fermented into small molecules of organic acids such as acetic acid, propionic acid, butyric acid, etc., and some gases such as methane, H2, CO2, etc. are produced, and most of these products can be Lactose reabsorbed by the colon, but not absorbed or still not decomposed can cause bowel, abdominal distension, abdominal pain, exhaust, discomfort, diarrhea and other symptoms, and some people may have hernia, nausea and so on. These symptoms are called lactose intolerance. The symptoms of lactose intolerance vary widely from individual to individual. Severe lactose intolerance occurs more than 30 minutes to several hours after ingesting a certain amount of lactose.
Cause
Cause
Lactase deficiency in the small intestine of neonates is the main cause.
1. Congenital lactase deficiency: refers to the low or lack of lactase activity at birth, which is caused by the recessive gene on the autosome of the body. This type is rare.
2, the lack of primary lactase: also known as the lack of adult lactase, is due to human generations of eating habits leading to genetic changes, incidence is related to age and ethnicity, most people belong to this type.
3, secondary lactase deficiency: refers to the temporary lactase activity caused by intestinal epithelial damage due to various reasons, common causes such as infectious diarrhea, recovery of the body disease can return to normal.
4. For children, multiple diarrhea and bacterial diarrhea in autumn may cause a temporary decrease in gastrointestinal function, decreased lactase secretion or decreased activity, and continuous lactation may cause secondary lactose intolerance.
5, large doses of the first cell, lactam antibiotics can also cause secondary lactose intolerance.
Examine
an examination
Related inspection
Blood routine abdominal CT duodenal drainage microscopy examination of gastrointestinal CT examination of gastrointestinal diseases by ultrasonography
Urine galactose test - urine galactose in the urine after drinking milk comes from the milk, so the detection of urinary galactose can detect the body's decomposition level of lactose, so as to determine whether lactose is tolerant.
Intestinal fungal disease detection - intestinal fungal disease is secondary to other diseases, can be caused by Candida, etc., can also be caused by thrush or Candida mucosa.
CT examination of the gastrointestinal tract - CT examination of the gastrointestinal tract is a method of examining the gastrointestinal tract by CT.
Duodenal barium meal angiography - angiography can show the shape of the duodenum, for the observation of the organic lesions of the duodenum, especially for the diagnosis of obstructive jaundice and lesions around the ampulla.
Small bowel angiography - angiography of the small intestine by X-ray examination.
Diagnosis
Differential diagnosis
Clinically, it is often distinguished from neonatal vomiting.
Neonatal vomiting refers to the reflex action of the contents of the stomach and a part of the contents of the small intestine in the digestive tract and discharged from the oral cavity. It is a manifestation of dysfunction of the digestive tract. The typical vomiting action has three steps: 1 creeping from the corpus to the lower end of the stomach to stay at the corner of the stomach, where there is a strong contraction, the stomach contents can not push down; 2 epiglottis close the soft palate up, make the pharynx Separated from the trachea and nasal passages; 3 open the esophagus, the esophageal relaxation of the diaphragm is fixed in the deep inhalation position, the abdominal muscles contract suddenly, and the contents of the stomach are squeezed through the esophagus to discharge the newborn. The vomiting action is not as typical as that of adults or children. To vomit after birth, vomiting after feeding is aggravated as non-ejection vomiting. The vomit is foamy mucus, and the blood containing the liquid is more than 1 to 2 days after birth. After the swallowed amniotic fluid and the contents of the birth canal are vomited, the vomiting disappears without other complications. The child is generally normal. Those who are not accompanied by cyanosis and cough are not required to be treated specially. In severe cases, 1% or 2 times of gastric lavage with 1% sodium bicarbonate can be cured.
Congenital and more familial. Neonatal diarrhea symptoms appear 1 to 2 hours after breastfeeding, accompanied by abdominal distension, hyperactivity of bowel sounds, spastic diarrhea, severe vomiting, loss of water, acidosis. The stool is watery, foamy, acidic, and contains lactose. Signs: weight loss, malnutrition, weight loss, anemia, abdominal swelling and so on.
In addition to gastrointestinal symptoms, there are systemic weakness, weakness, sweating, palpitations, aversion to cold, dizziness, headache, and sometimes pain in the anterior region and muscle contraction. Long-term adulthood of this disease can lead to osteoporosis due to calcium deficiency.
The primary symptoms are intestinal symptoms, which are manifested as symptoms of intestinal discomfort, such as abdominal distension, bowel, qi, abdominal pain, diarrhea, etc.
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