Varicella-like rash

Introduction The varicella-like rash lesion is mainly in the epidermal spine cells. Cell degeneration and edema form sac cells, the latter liquefy and tissue fluid infiltrate into vesicles, and there are hyperemia, monocytes and multinucleated giant cells infiltrating around and at the base, and eosinophilic inclusions in the nucleus of multinucleated giant cells. The blister contains a lot of virus. It is transparent at the beginning, and becomes turbid due to epithelial cell shedding and leukocyte invasiveness, and becomes pustule after secondary infection.

Cause

Chickenpox is a disease characterized by scattered blister and is highly contagious. It is more common in children. The amount of virus invaded into the blood first in the mononuclear phagocytic system, and then enters the blood circulation a lot, forming a second viremia, invading the skin and internal organs, causing the disease. Herpes zoster is characterized by clustering small blisters along the nerve and unilateral distribution, characterized by obvious neuralgia. It is more common in adults, and Chinese medicine is called tangled waist. Skin damage is superficial, leaving no scar after dislocation. Mucosal herpes is easy to form ulcers and is easy to heal.

an examination

Related inspection

FBC rose test solid phase enzyme immunoassay

Fever and rash (plaque, herpes) occur at the same time, or there is no fever and rash. The rash is distributed to the heart and is more common in the trunk, head and waist. The rash appeared in batches, maculopapular rash vesicular rash crusting, different forms of rash existed at the same time, no scars were left after the cap was removed. The symptoms are smaller and heavier. The prodromal period is long, the fever is high, the systemic symptoms are heavier, the number of rashes is more, and itching is more common. It is usually caused by the mother during production. The general symptoms are mild, but systemic damage can also occur.

Differential diagnosis

(1) Bullous varicella: only seen in children under 2 years of age. The blisters of 2 to 7 cm in size are formed in batches, and the erosion surface is formed after the ulceration, but the healing is rapid.

(2) Hemorrhagic varicella: The contents of the blister are bloody, with high fever and severe systemic symptoms. Occurs in patients with malnutrition, malignant lymphoma, leukemia and other immunosuppressive agents and corticosteroids.

(3) Newborn chickenpox: Usually it is infected by the mother during production. The general symptoms are mild, but systemic damage can also occur.

(4) Adult chickenpox: The symptoms are small and heavy. The prodromal period is long, high fever, systemic symptoms are heavier, the number of rashes is large, and it is more itchy.

Fever and rash (plaque, herpes) occur at the same time, or there is no fever and rash. The rash is distributed to the heart and is more common in the trunk, head and waist. The rash appeared in batches, maculopapular rash vesicular rash crusting, different forms of rash existed at the same time, no scars were left after the cap was removed.

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