High number of coffee milk spots

Introduction The coffee milk spots that exist alone are often only one type of birthmark, and have no adverse effect on human health. However, if the number of coffee milk spots is large and gradually becomes larger, it is necessary to be alert to the possibility of "neurofibroma". Neurofibromatosis, like milk coffee spots, is also a dominant genetic disease. The next generation of patients has a chance of recurring the disease about 1/2. The other half of the patients are caused by mutations in their own genes. They are not related to their parents. In addition to the age-related symptoms, the symptoms vary greatly among family members or different patients. Some people may only have coffee milk spots in their lifetime. However, some people have long appeared various neurofibromas and even malignant tumors.

Cause

Neurofibromatosis, like milk coffee spots, is also a dominant genetic disease. The next generation of patients has a chance of recurring the disease about 1/2. The other half of the patients are caused by mutations in their own genes. They are not related to their parents. In addition to the age-related symptoms, the symptoms vary greatly among family members or different patients. Some people may only have coffee milk spots in their lifetime. However, some people have long appeared various neurofibromas and even malignant tumors.

an examination

Related inspection

chromosome

Neurofibroma is a common hereditary disease with an incidence of about 1 in 3000. It is the most common clinical type. Before puberty, there were almost no other abnormalities in appearance except for the appearance of coffee milk spots on the skin. In the future, some patients will have neurofibromatosis of the skin or optic nerve tumor of the eye and tumors of various organs of the body. Sometimes, blood vessels may cause hypertension or affect bone growth and cause scoliosis. A few serious cases sometimes cause abnormal limb growth or lymphedema, which looks like an elephant's leg.

The method for judging whether a child with coffee milk spots develops into a neurofibromatosis is: 6 or more in the body (especially under the armpit), and the diameter is > 0.5 cm (before puberty) or > 1.5 cm (after puberty). When coffee milk spots, you should pay close attention to your child's nervous system, internal organs, eyes and other tumors, and whether the child's growth and development are abnormal, such as short stature, precocious puberty or mental retardation.

There are also some rare genetic or chromosomal diseases in the clinic, as well as coffee milk spots. Therefore, when there is a coffee milk spot on the child and there is a poor growth or other abnormal body, you should go to the hospital for examination.

Differential diagnosis

Differential diagnosis of a large number of coffee milk spots:

1, pigmentation spots: mixed sputum sputum cells and sputum cells nested deep in the epidermis also in the dermis called mixed sputum. Common central bulge highlights the leather surface, long hair, surrounded by diffuse distribution, different color, unclear boundary, is the boundary composition, the junction from childhood to the skin ,, so the elderly are rare mixed . Both mixed sputum and junction sputum may have malignant changes.

2, skin spot-like: skin spots are one of the clinical symptoms of sporadic dysentery. Patients in the neonatal period with or without jaundice continued, difficulty in sucking, constipation, poor breathing, snoring (nasal congestion, thick tongue), hoarseness, weak crying, less movement, bloating and skin spots.

3, skin dark spots: dark spots can be divided into congenital and acquired two kinds.

Neurofibroma is a common hereditary disease with an incidence of about 1 in 3000. It is the most common clinical type. Before puberty, there were almost no other abnormalities in appearance except for the appearance of coffee milk spots on the skin. In the future, some patients will have neurofibromatosis of the skin or optic nerve tumor of the eye and tumors of various organs of the body. Sometimes, blood vessels may cause hypertension or affect bone growth and cause scoliosis. A few serious cases sometimes cause abnormal limb growth or lymphedema, which looks like an elephant's leg.

The method for judging whether a child with coffee milk spots develops into a neurofibromatosis is: 6 or more in the body (especially under the armpit), and the diameter is > 0.5 cm (before puberty) or > 1.5 cm (after puberty). When coffee milk spots, you should pay close attention to your child's nervous system, internal organs, eyes and other tumors, and whether the child's growth and development are abnormal, such as short stature, precocious puberty or mental retardation.

There are also some rare genetic or chromosomal diseases in the clinic, as well as coffee milk spots. Therefore, when there is a coffee milk spot on the child and there is a poor growth or other abnormal body, you should go to the hospital for examination.

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.