Wide orbital distance

Introduction Due to mental retardation, mental retardation or obstruction, the mental function caused by mental retardation is significantly lower than the same age level, accompanied by a syndrome characterized by social adaptation difficulties. IQ (IQ) is lower than the population mean of 2.0 standard deviation (the IQ of the population is set at 100, the IQ value of a standard deviation is 15), and the general IQ below 70 (or 75) is that the intelligence is significantly lower than the average. It is manifested by an excessive widening of the bone distance between the inner walls of the eyes. There are two main reasons for mental retardation: 1 genetic factors; 2 environmental factors.

Cause

There are two main reasons for mental retardation: 1 genetic factors; 2 environmental factors.

Genetic factors include chromosomal aberrations and hereditary metabolite monogenic diseases; environmental factors include pregnancy, adverse factors during birth and harmful factors in newborns and infants.

In addition, due to the early cultural and emotional deprivation, lack of appropriate stimulation, long-term neglect and isolation, living in remote poverty, cultural backwardness, and inaccessible areas. The degree of mental retardation caused by general psychosocial factors is relatively low. Once the unfavorable factors are eliminated, it is possible to improve their intelligence level. The improvement depends on the age of the child, the degree of damage and the conditions provided by the environment.

an examination

Related inspection

Ophthalmic examination of the eye and sacral area CT examination

1. Blood: Hemoglobin is more than <60g l="">10%, visible red blood cell debris. Reticulocytes increase. There are inclusion bodies in the red blood cells. White blood cells and platelets are normal or reduced.

2. Bone marrow: hyperplasia, red blood cell line hyperplasia. Extracellular iron and iron granules increased.

3. Hemoglobin electrophoresis: hemoglobin F>30% (heavy -globin production barrier). Hemoglobin Bart>80% (hemoglobin Bart fetal edema syndrome); electrophoresis appeared hemoglobin H zone (hemoglobin H disease).

4. Conditional synthesis ratio and gene analysis of , globin peptide chain.

Differential diagnosis

It should be differentiated from the eyelid malformation caused by trauma.

The diagnosis is mainly based on the IOR (Interorbital distance) measurement.

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