Upper eyelid thickening and laxity

Introduction Patients with thick-skinned pericarposis have a head-like cranium, especially the upper eyelids are thick and slack, the ears and lips are also thick, especially large, and the skin of the hands and feet is also thick. The bones of the extremities and the phalanx are hypertrophied, the fingers and toes are sick, and the sacs and knee joints are effusion. The patient has pain in his limbs and his movements are awkward.

Cause

(1) Causes of the disease

The primary may be autosomal dominant. Secondary is also called hyperproliferative osteoarthrosis. Often secondary to a variety of chronic and malignant neoplastic diseases.

(two) pathogenesis

The pathogenesis is still unclear.

an examination

Related inspection

Eye external examination eyelid examination eyelid muscle force meter

According to the typical changes of skin and bone, it can be diagnosed. X-ray examination shows proliferative periostitis such as tibia, tibia, tibia and ulna, and diffuse periosteal thickening.

Differential diagnosis

Eyelid relaxation: blepharochalasis syndrome, also known as dermatolysis palpebrarum, atrophic eyelid ptosis (ptosis atrophica), is a rare eyelid disease characterized by recurrent episodes of eyelid edema in adolescents. The skin of the eyelids becomes thinner, the elasticity disappears, the wrinkles increase, and the color changes, which can be accompanied by clinical manifestations such as lacrimal gland prolapse, ptosis and shortening of the cleft palate. In 1807, Beer first described the disease. In 1896, Fuchs called it eyelid retardation. Because the syndrome affects the appearance of the eyelids, it is the main reason for patients to require treatment. The understanding of their clinical manifestations and pathogenesis can help to adopt appropriate methods for treatment.

Eyelid relaxation and upper lip thickening: characterized by loose eyelids and progressive thickening of the upper lip, it is called eyelid relaxation-upper lip hypertrophy syndrome, and some patients have goiter, also known as eye-mouth-thyroid syndrome. From the early onset, the eyelid edema began, after repeated episodes of eyelid skin relaxation, wrinkling, accompanied by telangiectasia, severe eyelid ptosis. From the infants and young children, the lips are repeatedly swollen, and the lips become fibrotic due to inflammation and become thicker into lips. Simple thyroid gland and swelling occur during puberty.

Eyelid closure is incomplete: the upper and lower eyelids cannot be completely closed, causing partial eyeball exposure, also known as rabbit eye. According to the clinical manifestations of the eye, it can be clearly diagnosed.

Eyelid drooping: also known as "hanging down." Due to insufficiency or disappearance of the levator palpebral function, or some or all of the upper jaw can not be lifted, the upper jaw is in a drooping position. Divided into complete and partial, monocular or binocular, congenital and acquired, true and false. If congenital, check whether: 1 simple ptosis (lifting or disappearing of the diaphragm function); 2 ptosis with upper rectus muscle function weakened; 3 ptosis with other ankle deformities, such as internal hemorrhoids Skin, etc.; 4 ptosis combined with (Marcus-Gunn) mandibular blinking movement phenomenon. If the nature is acquired, check whether: 1 traumatic eyelid or craniocerebral injury, or cervical sympathetic nerve injury; 2 disease such as myasthenia gravis; 3 mechanical such as trachoma sacral infiltration, or loss of support force of eyelids, If there is no eyeball. When there is suspected myasthenia gravis, it can be used as a test for neostigmine. When it is suspected of sympathetic drooping, it can be used as a test for hydroxyamphetamine.

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