Significant upper pulmonary fibrosis

Introduction The proliferation of fibrous tissue in organs or tissues, which causes a significant increase in collagen fibers, is called fibrosis. This change is most common in chronic inflammation caused by long-term effects of the cause. The two pulmonary fibrosis lesions generally refer to the lungs have been infected with tubercle bacilli, the basic pathological changes of tuberculosis have inflammation, hyperplasia, cheese-like necrosis.

Cause

1. Rheumatic immune chronic disease: systemic sclerosis, polymyositis/dermatomyositis, systemic lupus erythematosus, rheumatoid arthritis, mixed connective tissue disease, ankylosing spondylitis;

2, treatment of current or drug-related diseases: anti-arrhythmia drugs, anti-inflammatory drugs, anticonvulsants, chemotherapy drugs, vitamins, radiotherapy, oxygen poisoning;

3. Occupational and environmental related experience diseases: silicosis, asbestosis lung, heavy metal lung, coal dust pneumoconiosis, pneumoconiosis, alumina lung;

4. Inhalation of inorganic dust: talcum powder lung, iron pneumoconiosis, tin pneumoconiosis;

5. Inhalation of organic particles (allergic alveolitis): the lungs of the pigeons, the lungs of the farmers;

6, primary disease surgery (unclassified type), neoplastic disease: pulmonary lymphangiosis, bronchoalveolar carcinoma, pulmonary lymphoma, Kaposi sarcoma;

7. Idiopathic fibrotic diseases: idiopathic fibrosis, familial idiopathic pulmonary interstitial fibrosis, acute interstitial pneumonia, desquamative interstitial pneumonia, non-specific interstitial pneumonia, lymphocytes Interstitial pneumonia, autoimmune pulmonary interstitial fibrosis;

8, other: neurofibromatosis, tuberous sclerosis, sarcoidosis eosinophilic pneumonia, alveolar proteinosis, diffuse alveolar hemorrhage, alveolar microlithiasis, metastatic calcification.

an examination

Related inspection

Chest radiograph CT examination of diffusion volume

1. Clinical symptoms characterized by progressively worsening dyspnea.

2. The lungs have typical diffuse interstitial disease shadows.

3. No cause of illness was found.

4. Restrictive ventilation dysfunction, decreased diffuse function.

5. Lung biopsy can help diagnose the diagnosis.

Differential diagnosis

(1) Alveolar cell carcinoma: often occurs in middle-aged and elderly people, and is not closely related to smoking. The clinical manifestations are cough, cough, large amount of foam, chest tightness, shortness of breath, and the smell of wetness in the lungs during infection. The imaging can see two The lungs are diffusely interstitial, and the disease progresses rapidly. Tumor cells can be found by sputum or lung biopsy.

(2) Alveolar proteinosis: can occur at any age, more common in adults, male and female incidence is about 8:3, the cause of this disease is unknown. Clinical manifestations of progressive chest tightness, difficulty breathing, both lungs can be heard and wet voice, CT can be seen in the auxiliary road stone-like glass, alveolar lavage is milky white turbid liquid, PAS staining positive.

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