Thickening of the stomach wall

Introduction Thickening of the stomach wall is a common symptom of invasive gastric cancer. The infiltration of the tumor along the stomach wall causes thickening of the stomach wall, mainly due to the deep infiltration of the cancer along the stomach wall. Thickening of the stomach wall is often >1mm. The enhanced scan often shows abnormal enhancement of the stomach wall. The inner layer can be seen as a linear or strip-like enhancement shadow, which is called "white line disease". In a few cases, calcification is visible in the thickened stomach wall. .

Cause

1. Regional environment and dietary factors

There is a significant regional difference in the incidence of gastric cancer. The incidence of gastric cancer in the northwest and eastern coastal areas of China is significantly higher than that in the southern region. The incidence of distal gastric cancer is high in people who have been eating roasted and salted food for a long time, and it is related to the high content of carcinogens or pre-carcinogens such as nitrite, mycotoxins and polycyclic aromatic hydrocarbons in food; the risk of gastric cancer in smokers 50% higher than non-smokers.

2. Helicobacter pylori infection

The Hp infection rate of adults in high-risk areas of gastric cancer in China is above 60%. Helicobacter pylori can promote the conversion of nitrate to nitrite and nitrosamines, causing cancer; Hp infection causes chronic inflammation of gastric mucosa and environmental pathogenic factors accelerate the excessive proliferation of mucosal epithelial cells, leading to distortion and carcinogenesis; toxic products of Helicobacter pylori CagA and VacA may have a cancer-promoting effect, and the detection rate of anti-CagA antibodies in gastric cancer patients is significantly higher than that of the general population.

an examination

Related inspection

Stomach examination

A gastroscopy can be performed.

Differential diagnosis

Can be distinguished from the stiffness of the stomach wall.

The localized manifestations are abnormal thickening or disappearance of mucosal stenosis, localized gastric wall stiffness, and narrow gastric cavity fixation. In the same position and in different periods, the stomach wall may have double shadows, indicating that the normal peristaltic stomach wall and the stiff stomach wall are heavy. The widely infiltrated mucosal folds are flat or disappear, the gastric cavity is significantly reduced, the entire stomach wall is stiff, and no peristaltic waves are visible.

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