Upper body fat type

Introduction Progressive lipodystrophy is characterized by obesity in the upper body due to the disappearance of the patient's adipose tissue, special obesity and normal adipose tissue.

Cause

Mainly associated with hypothalamic lesions and post-ganglionic sympathetic neuropathy in parallel with the spinal nerve. The hypothalamus plays a regulatory role in gonadotropins, thyroid stimulating hormones and other endocrine glands, and is closely related to the post-ganglionic sympathetic nerve fibers. There seems to be a boundary between the disappearance zone of adipose tissue of the progressive lipodystrophy and the normal zone or the obese zone. This boundary has a certain relationship with the segment of the spinal cord. Usually, the body is divided into the upper body and the lower body with the waist 1 to 2 as the boundary. Two parts.

Another study suggests that the hypothalamic and pituitary constitute a metabolic regulation control system, and fat loss is related to the promotion of fat transfer factors produced by the system. Before the onset, there may be a history of acute fever and endocrine defects, such as hyperthyroidism, hypopituitarism and encephalitis. Injury, mental factors, early menstruation and pregnancy may all be incentives. At present, the view on the role of genetic factors has not been unified. .

an examination

Related inspection

Blood viscosity electromyogram

Laboratory tests revealed elevated serum chylomicrons, pre-beta lipoproteins, and triglycerides. 70% of patients had a decrease in C3 and 90% had a change in nephritis.

1. Skin and subcutaneous tissue biopsy showed subcutaneous adipose tissue atrophy and normal skin.

2. Electromyography shows normal muscle and nerves.

3. B-ultrasound can be found that the affected organs shrink and become smaller.

Differential diagnosis

According to different combinations, it can be expressed as the following types:

1 upper body is normal, lower body is obese;

2 upper body is thin, lower body is obese;

3 simple upper body weight loss type;

5 lower body weight loss type;

6 body weight loss type;

7 half-length obese.

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