Depigmentation

Introduction Skin pigmentation is a primary condition of vitiligo caused by a decrease or loss of function of the tyrosinase system in the melanocytes of the skin and hair follicles. Classification: vulgaris and segmental, vulgaris is divided into: localized, sporadic, generalized, and omnivorous. Classification: Complete leukoplakia and incomplete leukoplakia. Staging: active period, stable period.

Cause

It is not entirely clear that the doctrines related to the occurrence of this disease mainly include autoimmune theory, genetic theory, psychology, melanocyte self-destruction theory, keratinocyte dysfunction theory, and relatively lack of tyrosine and copper ions. The occurrence of vitiligo may be caused by genetically motivated individuals, induced by a variety of internal and external factors, abnormal immune function, neuropsychiatric and endocrine and metabolic abnormalities, resulting in inhibition of the tyrosinase system or destruction of melanocytes. Causes pigment loss.

an examination

Related inspection

Physical examination of skin lesions

According to the depigmentation, it is acquired, milky white, peripheral pigmentation zone and no symptoms. It can be diagnosed.

1. White epilepsy can occur in any part of the body. White spots occur in exposed areas such as the face, neck, waist and abdomen, appendix, forearm extension and finger back. There are no symptoms, but the rash on the sun may have a burning sensation and a chronic course.

2, the skin lesions are local pigmentation loss spots, the white hair inside the spots becomes white, the boundary is clear, and the area is red or blisters after sun exposure.

3, skin lesions can be seen in any part, mostly nails to coins, nearly round, oval, although later expanded or merged into an irregular large shape, but no matter how its shape changes, white spots are always visible, white spots There are island pigment spots in the middle; another typical white spot is a strip or strip-shaped depigmentation along the nerve, and the edges of the white spots are neatly cut like a knife.

Differential diagnosis

Skin pigmentation is bronze: Loss of salt nephritis has typical clinical manifestations of polyuria and nocturia, skin pigmentation is bronze, etc., salt-losing nephritis, also known as Thorn syndrome, is currently considered to be a group with severe renal Loss of salt is a special type of certain kidney disease characterized by it.

Cyan red complexion: Cyanine may be caused by fish caused by histamine poisoning. Since animals such as shrimp, crab, and squid die, the protein in the body rapidly decomposes, producing a large amount of histamine. Eating these aquatic products will increase the histamine content in the human blood. If you eat improperly or allergic to the face or even the skin color, it will appear blue-red, discomfort, and sometimes accompanied by headache and itching.

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