Gene fusion

Introduction The so-called fusion gene refers to the chimerism of the coding regions of two or more genes, which are placed under the control of the same set of regulatory sequences (including promoters, enhancers, ribosome binding sequences, terminators, etc.). The expression product of the gene. fusion gene is a fusion protein.

Cause

Some causes are unknown, but there are reports of genetic and viral cancer cells. But more is artificial genetic fusion. The so-called fusion gene refers to the chimerism of the coding regions of two or more genes, which are placed under the control of the same set of regulatory sequences (including promoters, enhancers, ribosome binding sequences, terminators, etc.). The expression product of the gene. fusion gene is a fusion protein.

an examination

Related inspection

Multidrug resistance (MDR) gene detection CT examination

The chimeric gene consisting of two or more gene coding regions end-to-end and placed under the control of the same set of regulatory sequences (including promoters, enhancers, ribosome binding sequences, terminators, etc.) and successfully expressed Fusion protein.

Differential diagnosis

Gene mutation: A change in the structure of a gene caused by the addition, deletion or alteration of a base pair in a DNA molecule is called a gene mutation. The chimeric gene consisting of two or more gene coding regions end-to-end and placed under the control of the same set of regulatory sequences (including promoters, enhancers, ribosome binding sequences, terminators, etc.) and successfully expressed Fusion protein.

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