Toxemia of pregnancy

Introduction Toxemia in pregnancy is a syndrome of ketosis, acidosis, hypoglycemia and liver failure. Most occur in the middle and late pregnancy. The occurrence of this disease is firstly the consumption of liver glycogen in the body, and then mobilize body fat to regulate the blood glucose balance, resulting in a large amount of fat accumulating in the liver and free in the blood, causing fatty liver and hyperlipidemia, liver failure, organic ketone A large amount of organic acid accumulates, leading to ketonemia and acidosis. Mainly related to malnutrition and lack of exercise. Varieties, age, obesity, parity, excessive pregnancy, excessive fetal, malnutrition during pregnancy and environmental changes can affect the occurrence of this disease.

Cause

The cause is not fully understood and is currently thought to be mainly related to malnutrition and lack of exercise. Age, obesity, parity, excessive pregnancy, excessive fetal, malnutrition during pregnancy and environmental changes can affect the occurrence of this disease.

The occurrence of this disease is firstly the consumption of liver glycogen in the body, and then mobilize body fat to regulate the blood glucose balance, resulting in a large amount of fat accumulating in the liver and free in the blood, causing fatty liver and hyperlipidemia, liver failure, organic ketone A large amount of organic acid accumulates, leading to ketonemia and acidosis. When a large amount of ketone bodies are excreted through the kidneys, the kidneys are fatty degenerated, and toxic substances are even more unremovable, causing uremia. At the same time, hypoglycemia occurs because the body cannot complete the regulation of glucose balance. Therefore, pregnancy toxemia is a syndrome of ketosis, acidosis, hypoglycemia and liver failure.

an examination

Related inspection

Blood test, urine routine, empty sign

Symptoms: mild symptoms are not obvious, severe cases can be depressed, breathing difficulties, severe urine output, exhaled gas with ketone. Abortion, ataxia, convulsions and coma can occur before death. Hematological examination showed an increase in non-protein nitrogen, decreased calcium, increased phosphorus, and positive acetone test.

Diagnosis: According to the symptoms and medical history, combined with hematological examination can confirm the diagnosis.

Differential diagnosis

Differential diagnosis of pregnancy toxemia:

Pregnancy toxemia occurs in the first 3-4 months of pregnancy or during childbirth and 48 hours after delivery. It is characterized by high blood pressure, edema and proteinuria. Severe convulsions, coma. If blood pressure is increased early in pregnancy, it may be hypertension or secondary hypertension combined with pregnancy. More history of hypertension, urinary protein is lighter, can be identified. However, patients with hypertension often have hypertension and urinary changes during pregnancy. There are also statistics showing that about 30% of hypertensive patients with pregnancy have pregnancy toxemia, which can be considered when diagnosed.

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