Cord blood

Introduction Umbilical cord blood is the blood that remains in the placenta and umbilical cord after the baby is delivered, the umbilical cord is ligated and disconnected, and is usually discarded. Studies in the past decade have found that cord blood contains hematopoietic stem/progenitor cells that can reconstitute human hematopoiesis and immune system, and can be used for hematopoietic stem cell transplantation to treat various diseases. Therefore, cord blood has become an important source of hematopoietic stem cells, especially the source of unrelated hematopoietic stem cells. It is also a very important human biological resource. Hematopoietic stem cells in cord blood can be used to treat a variety of blood system diseases and immune system diseases, including hematological malignancies (such as acute leukemia, chronic leukemia, multiple myeloma, myelodysplastic syndrome, lymphoma, etc.), hemoglobin Disease (such as maritime anemia), bone marrow hematopoietic failure (such as aplastic anemia), congenital metabolic disease, congenital immunodeficiency disease, autoimmune disease, certain solid tumors (such as small cell lung cancer, neuroblasts) Tumor, ovarian cancer, etc.). Beijing cord blood hematopoietic stem cell bank has successfully provided cord blood hematopoietic stem cells for many patients. Only 30 patients with leukemia have been transplanted and treated at Peking University People's Hospital and Peking University Institute of Hematology. The implantation rate is 83%. . One case of leukemia patients weighed 95kg, and the preservation quality and transplant success rate of cord blood have reached the world advanced level.

Cause

Umbilical cord blood hematopoietic stem cells are important personal biological resources that the child has only one chance to keep in his lifetime. Storing the child's cord blood is equivalent to storing a child's life backup. Cord blood is not only effective in treating dozens of refractory diseases. And a variety of incurable diseases, and the types of diseases it can treat are constantly increasing. When the cord blood stored by the body is used, it does not need to be matched, the cell activity is strong, there is no risk of immune rejection, the graft survival rate is high, the cure rate is high, the medical cost is low, and the stored cord blood can also have other members of the family. A certain guarantee. From the perspective of future development, cord blood stem cells have extremely high medical value: it will be the seeds of organ cloning; the means of repairing aging tissues and organs, resisting human aging; it is a weapon to overcome cancer; the treatment of nerve spinal cord injury has also entered the clinical Test phase.

an examination

Umbilical cord blood collection has no effect on maternal and newborn. HLA does not need to be completely matched during cord blood transplantation, and 75% of opportunities are suitable for use among siblings. The chances of suitable use among non-relatives are also greatly increased. Less rejection occurs, and to a lesser extent.

The existing experimental data show that umbilical cord blood hematopoietic stem cells still have good activity after more than ten years of cryopreservation. The preservation history of umbilical cord blood has been nearly twenty years, and theoretically it can be preserved for a long time. The latest modern preservation technology has not been compared with the previous preservation technology. Under the previous preservation technology, hematopoietic stem cells have been preserved for more than 40 years. The preservation history of common tissue cells has been more than 100 years. The latest preservation technology has been used. Program-controlled cooling, adding intracellular and external protective agents to overcome the problem of cell damage in the past freezing, Beijing cord blood hematopoietic stem cell bank is the most advanced stem cell preservation technology in the world, so from the preservation technology, Cord blood hematopoietic stem cells can be preserved in the cord blood bank for a long time.

Differential diagnosis

Embryonic stem cells: Embryonic stem cells have been shown to be transformed into any type of cell and can be used to transplant all tissues or systems of the human body, replacing the original "lesion" tissue or system. Umbilical cord blood stem cells are considered to be an adult stem cell, although commercial companies have advertised that future cord blood stem cells may be converted to nerve, liver and heart cells to treat these diseases, but this hypothesis is far from being confirmed by scientific experiments. Currently, cord blood stem cells can only be considered useful only when replacing hematopoietic and immune cells.

Hematopoietic stem cells in cord blood can be used to treat a variety of blood system diseases and immune system diseases, including hematological malignancies (such as acute leukemia, chronic leukemia, multiple myeloma, myelodysplastic syndrome, lymphoma, etc.), hemoglobin Disease (such as maritime anemia), bone marrow hematopoietic failure (such as aplastic anemia), congenital metabolic disease, congenital immunodeficiency disease, autoimmune disease, certain solid tumors (such as small cell lung cancer, neuroblasts) Tumor, ovarian cancer, etc.). Beijing cord blood hematopoietic stem cell bank has successfully provided cord blood hematopoietic stem cells for many patients. Only 30 patients with leukemia have been transplanted and treated at Peking University People's Hospital and Peking University Institute of Hematology. The implantation rate is 83%. . One case of leukemia patients weighed 95kg, and the preservation quality and transplant success rate of cord blood have reached the world advanced level.

Umbilical cord blood hematopoietic stem cells are important personal biological resources that the child has only one chance to keep in his lifetime. Storing the child's cord blood is equivalent to storing a child's life backup. Cord blood is not only effective in treating dozens of refractory diseases. And a variety of incurable diseases, and the types of diseases it can treat are constantly increasing. When the cord blood stored by the body is used, it does not need to be matched, the cell activity is strong, there is no risk of immune rejection, the graft survival rate is high, the cure rate is high, the medical cost is low, and the stored cord blood can also have other members of the family. A certain guarantee. From the perspective of future development, cord blood stem cells have extremely high medical value: it will be the seeds of organ cloning; the means of repairing aging tissues and organs, resisting human aging; it is a weapon to overcome cancer; the treatment of nerve spinal cord injury has also entered the clinical Test phase.

Umbilical cord blood collection has no effect on maternal and newborn. HLA does not need to be completely matched during cord blood transplantation, and 75% of opportunities are suitable for use among siblings. The chances of suitable use among non-relatives are also greatly increased. Less rejection occurs, and to a lesser extent.

The existing experimental data show that umbilical cord blood hematopoietic stem cells still have good activity after more than ten years of cryopreservation. The preservation history of umbilical cord blood has been nearly twenty years, and theoretically it can be preserved for a long time. The latest modern preservation technology has not been compared with the previous preservation technology. Under the previous preservation technology, hematopoietic stem cells have been preserved for more than 40 years. The preservation history of common tissue cells has been more than 100 years. The latest preservation technology has been used. Program-controlled cooling, adding intracellular and external protective agents to overcome the problem of cell damage in the past freezing, Beijing cord blood hematopoietic stem cell bank is the most advanced stem cell preservation technology in the world, so from the preservation technology, Cord blood hematopoietic stem cells can be preserved in the cord blood bank for a long time.

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