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Subcutaneous fat disappears

Introduction
Cause
Examine
Diagnosis

Introduction

Introduction Lipoatrophy: The occurrence may be related to the patient receiving subcutaneous or intramuscular corticosteroids. Subcutaneous fat atrophy mainly manifests as the disappearance or weight loss of progressive subcutaneous fat tissue, which may cause skin wrinkles and depression, difficulty in pinching, often on the face, and then affect the neck, shoulders, arms and trunk, some patients disappear only fat Limited to the face or half-side, half body, muscle, bone, hair, breast and sweat glands are normal, no muscle disorders, most physical strength is not affected. Most of the disease occurs around the age of 5-10, and women are more common.

Cause

Cause

(1) Muscle atrophy caused by diseases such as systemic dystrophies, disuse, endocrine abnormalities, muscle degeneration, and abnormal muscle structure.

(2) Muscle atrophy caused by genetics, poisoning, metabolic abnormalities, infections, allergies, etc.

Examine

an examination

Related inspection

Serum cholesterol ester urine routine blood routine serum cholesterol and phospholipid ratio

Seen at any age. More common in the trunk. Subcutaneous fat is limited to local atrophy, the skin texture is normal, the pores are normal, and the skin is close to the sarcolemma below it.

Diagnosis

Differential diagnosis

Progressive lipodystrophy is a rare autonomic nervous system disorder characterized by adipose tissue metabolic disorders. The clinical and histological features are slowly progressive bilateral distribution with substantially symmetrical, well-defined, subcutaneous adipose tissue atrophy or Disappeared, sometimes combined with limited adipose tissue hyperplasia, hypertrophy.

Most patients start from around 5 to 10 years old, women are more common, and the onset and progress are slower. At the beginning of the disease, the facial tissue or upper extremity adipose tissue disappeared, and then expanded downward, involving the buttocks and thighs, showing a roughly symmetrical distribution. The course of the disease lasts for 2 to 6 years and can be stopped by itself. The patient's facial expression is concave on both sides of the cheeks and ankles, the skin is slack, and the normal elasticity is lost. The disappearance of fat around the cheeks and eyelids gives the patient a special face. Some patients may have obvious subcutaneous tissue hyperplasia and hypertrophy in the buttocks and hips, but the hands and feet are often unaffected.