Noncaseating granulomas of the skin

Introduction Non-eosinophilic granulomatous prostatitis is a non-cheese granuloma, which is centrally liquefied and necrotic. There are major tissue cells in the proximal gland lumen, surrounded by lymphocytes, plasma cells and eosinophils.

Cause

The cause of non-eosinophilic granulomatous prostatitis may be a foreign body tissue reaction of extravasation of prostatic fluid. The disease is characterized by rapid progression of these symptoms and the rapid development of urinary retention. Non-eosinophilic granulomatous prostatitis often occurs in the elderly, which is caused by the prostate's reaction to the foreign body such as bacterial products in the tissue.

an examination

Related inspection

Prostate examination, urinary system, CT examination, urine routine

Clinical manifestations:

Clinical symptoms of non-eosinophilic granulomatous prostatitis include symptoms of urinary tract infection, symptoms of bladder outlet obstruction, such as fever, chills, frequent urination, urgency, dysuria, occasional hematuria, perineal pain and discomfort, poor urination, urine Fine lines, urinary weakness and post-urine drip.

diagnosis:

Yellow, small, hard nodules are visible on the prostate section. Microscopically changed to non-cheese granuloma, its central liquefaction necrosis, the main tissue cells in the proximal gland lumen increased, surrounded by lymphocytes, plasma cells and eosinophils. Epithelial cells are often confused with cancer, in addition to Langerhans cells and foreign body giant cells. Semen is seen in the phagocytic cells, and the granuloma contains fat and foam inclusions.

Differential diagnosis

Sexually transmitted lymphogranuloma, also known as inguinal lymphogranuloma, is a sexually transmitted disease caused by infection with Chlamydia trachomatis. The disease usually occurs in tropical and subtropical regions of the world, especially in South America, Africa and Southeast Asia.

Eosinophilic granuloma (EG) is an abnormal differentiation of non-tumor properties of isolated tissue cells. Eosinophilic granuloma is a manifestation of Langerhans cell hyperplasia, formerly known as histiocytosis X. Eosinophilic granuloma occurs mostly in children 5-10 years of age, with parts of the bones and lungs. This accounts for 60-80% of cases of Langerhans cell hyperplasia. Blacks are rare.

In the past, sputum buds have been mistakenly referred to as sputum-like bacteriosis, and have been confirmed to be a tumor that originates in cutaneous helper T lymphocytes. It occurs mostly in young adults, but it also occurs in people over 10 years old or 60 years old, with more men than women. There are three types, the most common of which is the development of tumors from plaques or plaques, or tumors directly, called sudden sputum granuloma, which develops rapidly and has a poor prognosis. About 10% of cases can develop erythroderma, called erythrodermic mycosis fungoides. The disease can last from a few months to several years, with an average of 4-10 years.

Granuloma annulare is a benign inflammatory skin lesion of unknown etiology that occurs in the dermis or subcutaneous tissue and is characterized by ring-shaped papules or nodular lesions.

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