Immunodeficiency

Introduction Immunodeficiency is a kind of repeated infection or serious infectious disease caused by the development of the body's immune system deficiency or immune response disorder, resulting in low anti-infective ability. Immune defects are divided into primary and secondary types. The former is mainly found in infants and children. If a child has repeated infection after birth, he should go to the hospital to check the immune function and determine whether there is an immune defect. Children with immunodeficiency cannot be vaccinated with various live vaccines, which may have serious consequences.

Cause

1. Infection: Many viruses, bacteria, fungi and protozoal infections can often cause low immunity. For example, measles virus, rubella virus, cytomegalovirus, severe tuberculosis or leprosy infection can cause T cell function decline in patients, especially HIV-induced AIDS is the most serious.

2. Malignant tumors: Malignant tumors, especially lymphoid tissues, can often progressively inhibit the immune function of patients. Significant cellular immunity and humoral immune dysfunction often occur in cancer patients with extensive metastases.

3. Loss of protein, excessive consumption or insufficient synthesis: In the case of chronic glomerulitis, nephrotic syndrome, acute and chronic digestive tract diseases, and extensive burns or burns, proteins, including immunoglobulins, are lost in large amounts, and in the case of chronic wasting diseases Increased protein consumption, insufficient absorption of protein in the digestive tract and inadequate nutrition.

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Body function and nutrition

The role of immunity is to identify and exclude foreign substances in order to maintain the physiological balance and stability of the body. The results after the immune response are beneficial to the body under normal conditions, but under certain conditions, they can be harmful. The main function of immunity is to eliminate pathogens or antigenic substances. It is a manifestation of anti-infection process. It removes aging, denaturing cells and some waste materials in the body. It is a stable expression to maintain the balance of the environment in the body, and carries out immune surveillance to eliminate denatured cells. More common to eliminate cancer cells.

Differential diagnosis

Cell-deficient diseases are simple T cell immunodeficiency, which is often accompanied by different degrees of humoral immunodeficiency. This is because the formation of normal antibodies requires the cooperation of T and B cells, the occurrence of T cell immunodeficiency disease and thymic development. Bad about.

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