Neutropenia

Introduction White blood cells can be divided into two categories according to morphological differences: granules and non-granules. The white blood cells without particles have lymphocytes and monocytes. Granular leukocytes (granulocytes) contain special stained particles, which can be distinguished by staining with Wright's dye to distinguish three kinds of white blood cells, ie, neutrophils, eosinophils, and basophils. Non-granular leukocytes include monocytes and lymphocytes. The vast majority of granulocytes are neutrophils.

Cause

The decrease in the number of bloody white (granulocyte) cells often increases the patient's susceptibility to bacterial and fungal infections.

an examination

Related inspection

Neutrophil bactericidal test granulocyte to red blood cell ratio

The clinical manifestations are mainly primary disease. The majority of leukopenia patients are often short-lived, self-limiting, with no obvious clinical symptoms or non-specific manifestations such as dizziness, fatigue, hypothermia, and pharyngitis. Neutrophils are the first line of defense against infection, so the clinical symptoms of neutropenia are mainly susceptible to repeated infections. The risk of infection in a patient is directly related to the neutrophil count, the time of reduction, and the rate of reduction. Neutrophilia is the absolute value of the circulating polymorphonuclear nucleus (PMN) in the blood circulation pool.

Differential diagnosis

Elevate

Found in allergic diseases [asthma, urticaria, bronchopulmonary aspergillosis, allergies (ac eosinophils up to 8%-29%), eczema], certain drug reactions (penicillin, streptomycin, erythromycin, opioids, etc.) , parasitic diseases, nodular periarteritis and Voisins syndrome, skin diseases, hematological malignancies and neobiological disorders (sarcoidosis, Hodgkin's disease, primary polycythemia, liver cancer, ovarian cancer, pith Leukemia), ray, benzene, scarlet fever (8% to 20% eosinophils), hyperthyroidism, endocarditis and cardiomyopathy.

2. Reduce

Eosinophilia is seen in typhoid fever, acute malaria, diabetic acidosis, suprarenal hyperfunction, Surrenales, and stress.

[Elevation of eosinophils is generally associated with allergies (eg, asthma, urticaria) and parasitic infections. Some skin diseases such as eczema and blood diseases can also be caused, and are also associated with infectious diseases. In short, an increase in eosinophils alone cannot diagnose the disease. ]

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