Giant tongue

Introduction Giant tongue disease is a kind of benign tumor, mainly due to amyloidosis. It refers to the lesion caused by amyloid deposition on the skin or internal organs, which can cause the function of the deposition site to be disordered. It is a metabolic disorder. The tongue is a good site for this disease. The middle-aged and above populations have more incidences, and young people have occasional occurrences. The chemical reaction of this particular protein substance is similar to the starch, which turns blue into iodine and is therefore named "amyloid". At present, there is no specific drug treatment for the amyloidosis of the tongue. Prevention should be strengthened.

Cause

Giant tongue disease is divided into:

1 primary tongue amyloidosis: may be related to heredity, data statistics 30% to 60% of patients have a family history. Its pathogenesis is related to repeated mechanical stimulation (such as poor prosthesis), trauma, drugs and so on.

2 secondary amyloidosis: associated with long-term, chronic infections with severe tissue damage (such as tuberculosis, connective tissue disease, malignant tumors, etc.).

an examination

The main symptom of the amyloidosis of the tongue is the giant tongue. Clinical examination shows that the tongue is thickened and thickened to twice the normal tongue. The tongue is widely symmetrical and the teeth are printed on both sides of the tongue. The giant tongue causes dysfunction of the tongue, and symptoms such as unclear language and difficulty in swallowing occur. The back of the tongue (above) may have small nodules like pomegranate seeds, or bleeding or purpura. The patient has obvious tongue pain. Secondary infection occurs, and the tongue may have congestion and suppurative necrosis. As the tongue grows, thickens, and hardens, language dysfunction is aggravated. In severe cases, amyloid deposits may also be present in the lips, cheeks and gums. Clinically, in order to confirm the diagnosis, thickened gingival tissue is often taken for biopsy, and the final diagnosis is made by pathological diagnosis. Laboratory examination showed a decrease in serum albumin, an increase in globulin, and a coagulating protein in the urine.

The back of the tongue (above) may have small nodules like pomegranate seeds, or bleeding or purpura. The patient has obvious tongue pain. Secondary infection occurs, the tongue is widely symmetrical and the teeth are printed on both sides of the tongue.

Differential diagnosis

The symptoms of the giant tongue need to be identified as follows:

1, papilloma: occurs mostly at the edge of the tongue, the back of the tongue, the back of the tongue is rare, the surface of the mucosa has small nipples, external protrusion, 2 ~ 4cm, the edge is clear, the surrounding tissue is soft, the base is not infiltrated, need surgical resection.

2, hemangioma: a longer period of time, more often found in infants and young children, occurs in the lips, cheeks, tongue and other parts, mostly cavernous hemangioma, can be multiple hair, multiple hair, different sizes, different shapes, can Light and deep, the surface mucosa is smooth, mostly purple, soft, compressive, depending on the condition, surgical resection or sclerotherapy injection or liquid nitrogen freezing treatment.

3, lymphangioma: common in children, adolescents, occurs in the tongue, lips, cheeks and other parts, the tongue occurs in the back of the tongue, the tumor is mostly diffuse, into a small papillary mass, shiny, Micro-protruding the tongue, the surface is not flat, slightly lighter than the tongue. Because it often coexists with hemangioma, it can be seen that red or purple red particles or nodules are mixed. Lymphangioma is non-compressive, and the tumor becomes harder after repeated infections. Need surgical resection.

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