Shoulder girdle 'simulates paralysis'

Introduction Pediatric cooking syndrome clinical manifestations of upper limb paresthesia, secondary and triceps pain, shoulder strap "simulation". Cooks syndrome was first reported by Kwork. After eating Chinese food, a group of complex symptoms, neck, upper chest, back and arms were "burned", "pressed", "tightened" or "numb". Feeling or generalized burnout, accompanied by palpitations of palpitations, known as Chinese restaurant syndrome. Its alias is still delicious syndrome, Chinese headache, eating Chinese food syndrome, Japanese restaurant syndrome. In the past, there was also a syndrome called glutamate intake.

Cause

(1) Causes of the disease

The cause of this disease is unknown, and it is related to eating Chinese food.

(two) pathogenesis

1. Ingestion of Chinese food: Some scholars believe that high sodium in Chinese food produces temporary hypernatremia, which causes low potassium in the cells, leading to muscle paralysis, weakness, palpitations, thirst and vascular headache. Many reports suggest that oral monosodium glutamate (monosodium glutamate MSG) is the cause of this disease. Previous trials have shown that a single intake of MSG more than 1.5g can cause disease (most people take 5 ~ 6g, up to 12g), and the threshold of onset of intravenous injection of MSG is 125mg, the greater the intake of symptoms The heavier. In the investigation, some people still had no disease after eating 21g of MSG. Ghadimi et al. believe that:

1 The symptoms are similar to the symptoms and signs induced by acetylcholine; 2 The role of anticholinergic agents and cholinesterase inhibitors, supporting the hypothesis that this symptom is a "temporary" acetylcholine disease; 3 in the induction of acetylcholineemia, plasma gallbladder The alkali esterase activity pattern resembles the pattern after ingestion into MSG. Gore et al. believe that it is not simply due to the intake of MSG, but the result of ingestion of MSG and other unrecognized substances, or the result of ingestion of certain substances that are completely unrelated to MSG.

2. Genetic factors: There are also hereditary and individual differences. L-glutamate is a neuro-humoral transmitter with a large central nervous system and is harmless to the human body. However, when the animal is given a large amount of L-glutamic acid, it has various effects: the white mice can cause necrosis of the brain, especially the hypothalamus; the mature mice can cause obesity and endocrine gland lesions; for rats and mature dogs, it can cause Abnormal sleep EEG and myoclonic seizures as well as abnormal electroencephalograms of tonicity and even clonic convulsions. In addition, it has been shown that pyridoxine (vitamin B6) can aggravate this abnormal change. This may be a metabolic abnormality of -aminobutyric acid (GABA) and pyridoxine phosphate after a large intake of L-glutamic acid, but its effect on the human body is not necessarily the same as that of animals.

In 1993, the 19th meeting of the UN Food and Agriculture Organization of Food Additives announced that MSG is harmless. Can be removed from the previous regulations on adult food MSG restrictions, to determine that it is a reliable food additive, except for infants within 1 year of age, other age groups are edible. This conclusion is based on extensive research. The investigation found that the "Chinese restaurant syndrome" was not caused by the Chinese cuisine with more MSG, but by the contamination of the food by Bacillus cereus. The performance of MSG is stable under cooking temperature conditions, and there is no need to worry about deterioration and toxicity.

an examination

Related inspection

Electrocardiogram CT examination blood routine

1. Blood routine.

2. Urine routine.

3. Feces routine.

4. Cardiac EEG, CT examination.

Differential diagnosis

The differential diagnosis of the shoulder strap "simulation":

This symptom has neither fever nor diarrhea, but is characterized by neurological symptoms. Comprehensive medical history and epidemiological investigation data should be combined with acute food poisoning and food allergy.

Acute food poisoning: Food poisoning refers to acute toxic diseases caused by eating foods that are not conducive to human health. It is caused by eating food contaminated with bacteria and chemical poisons, or eating foods that are poisonous. Food poisoning is characterized by short incubation periods, sudden and collective outbreaks, most of which are symptoms of gastroenteritis and are clearly associated with the consumption of certain foods.

Food allergy: food allergy (foodallergy) or food allergy (allergicreaction of differential system), allergic gastroenteritis, etc., is caused by IgE mediated by certain foods or food additives. And non-IgE-mediated immune responses leading to allergic reactions in the digestive system or systemic.

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