Nasal congestion with purulent or bloody discharge

Introduction Churgstrauss syndrome (CSS), also known as allergic granulomatous vasculitis or allergic granulomatous vasculitis is a systemic necrotizing vasculitis involving the small and medium arteries and veins. The pathological feature is that the affected tissue has A large number of eosinophil infiltration and extravascular granuloma formation and necrotizing vasculitis. The earliest Churg and Strauss first reported 13 cases of asthma, eosinophilia, granulomatous inflammation, necrotizing systemic vasculitis, and necrotizing glomerulonephritis in 1951, hence the name. The Chapel Hill Conference in 1993 defined Churg-Strauss syndrome as a necrotic vessel with moderate to large blood vessels that is associated with asthma and eosinophilia involving the respiratory tract, a large number of eosinophilic infiltration and extravascular granuloma formation. inflammation. Allergic rhinitis is often the initial symptom of CSS, accompanied by recurrent sinusitis and nasal polyps, the main symptom is nasal congestion, discharge of purulent or bloody secretions.

Cause

The cause is still unclear, and it may be the same as other systemic vasculitis. The pathogenesis is related to immune abnormalities, especially allergies.

an examination

Related inspection

Gleogram of glomerular filtration (GFF) in nasopharyngeal MRI

See nasal cavity to exclude purulent or bloody secretions.

Differential diagnosis

CSS should be distinguished from other systemic, necrotizing vasculitis, with certain diseases of peripheral blood eosinophilia such as hypereosinophilic syndrome and bronchial asthma or wheezing bronchitis.

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