Mild steatosis of the liver

Introduction The liver is the hub of fat metabolism, and any obstacle in the process of fat metabolism can cause fatty degeneration of liver cells. The reasons are: lipoprotein synthesis disorders, excessive neutral fat synthesis, fatty acid oxidation or ester lipid disorders. When the liver develops steatosis, it is light, and there is no obvious abnormality in the eye. When it is severe, the liver is swollen, the texture is soft, the color is yellowish to yellow, the structure of the cut surface is fuzzy, there is greasy feeling, and some are even crispy. Microscopically, vacuoles of different sizes appear in the denatured hepatocyte cytoplasm, which are mostly seen around the nucleus. Later, they become larger and denser in the whole cytoplasm. In severe cases, they can fuse into a large vacuole, resembling an adipocyte. .

Cause

The reasons are: lipoprotein synthesis disorders, excessive neutral fat synthesis, fatty acid oxidation or ester lipid disorders.

an examination

Related inspection

Ultrasound diagnosis of liver, gallbladder and spleen by liver disease

1. Frozen slices, lipid droplets can be dyed orange in Sudan.

2, laboratory examination, imaging examination: blood routine, liver function, liver B ultrasound, CT, liver biopsy.

Differential diagnosis

Identification:

Liver ascites: cirrhosis ascites commonly known as liver ascites. Normal people have a small amount of free ascites in the abdominal cavity, usually about 50 ml, which plays a role in maintaining the lubrication between organs. When there is too much free liquid in the abdominal cavity, it is called ascites. Cirrhosis ascites is a chronic liver disease. From large, nodular, diffuse hepatic changes, necrosis, regeneration; regeneration, necrosis, promote tissue fibrosis and scar contraction, resulting in liver hardening, cirrhosis. Liver cirrhosis caused by portal hypertension, resulting in splenomegaly, protein fluid leaking from the absorption of protein and vitamins, formed ascites.

Liver lesions are diffuse: a manifestation of liver tissue lesions in imaging studies, also known as liver fibrosis. Hepatic fibrosis is an excessive deposition of diffuse extracellular matrix in the liver. It is the result of a large amount of collagen deposited in the hepatic cell space stimulated by activated hepatic stellate cells under the stimulation of various pathogenic factors. If the fibrous tissue continues to proliferate, invade the liver cells, destroy the structure of normal liver tissue, form many nodules surrounded by fibrous tissue, and the liver texture becomes hard, which is cirrhosis.

Hepatic rupture of the hepatic membrane: rupture under the capsule, rupture of the liver parenchyma under the capsule, formation of a subdural hematoma is a kind of liver rupture, liver rupture refers to liver rupture caused by blunt action. Since the external force acts directly on the liver area, the liver is squeezed between the anterior and posterior abdominal wall and the spine, or the body can be damaged by acceleration, deceleration, and torsion during exercise.

Hepatic steatosis: lipid droplets appearing in the cytoplasm beyond the physiological range, or fat droplets appearing in cells that do not normally have lipid droplets, which is called steatosis. The liver is the main organ of fatty acid metabolism, and liver fat is more common. In severe cases, almost all liver cells undergo fatty changes, liver enlargement, mild tenderness and abnormal liver function, called fatty liver.

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