Nasolabial fold redness and chapped

Introduction Facial seborrheic dermatitis can cause red and cleft palate in the nasolabial fold. At the beginning, the nasolabial folds are red, and the miliary size papules are stacked. It should be related to the effects of excessive secretion and allergic factors. It is thought to be related to factors such as heredity, changes in sebum metabolism, microbial parasitism, neurological dysfunction, and eating habits. It has been speculated that the occurrence of this disease is due to increased sebum secretion and changes in chemical composition, so that the normal flora originally present on the skin grows and multiplies and invades the skin.

Cause

Recent literature reports that the disease is due to the rapid growth of the epidermis, the lack of sufficient time for the stratum corneum cells to fully mature, resulting in the nucleus of the cell nucleus.

(1) Causes of the disease

The disease is caused by multiple factors. Related to age and gender, most cases have a genetic predisposition, and the level of androgen is increased, resulting in increased sebum secretion. In addition, seborrhea often occurs in neurological diseases such as Parkinson's disease (Pakinson syndrome), especially in the disease progression, sebaceous gland secretion levels can be 2 times higher than normal; in arteriosclerosis, diabetes, adrenal tumors, certain breast cancer Patients and patients with epilepsy also have increased sebum secretion.

(two) pathogenesis

This disease is a secondary inflammation that occurs on the basis of seborrhea. Recently, it has been suggested that due to increased sebum secretion and other chemical changes, the primary infection and secondary allergy caused by the growth and reproduction of P. ovale invading the skin are related to the congenital seborrheic quality, but the genetic pattern is unknown. . In addition, sebum overflow increases the body's susceptibility to bacteria, such as the non-pathogenic acne corynebacterium present on the skin, which multiplies and decomposes free fatty acids to cause inflammation. Sebaceous gland suppuration is also one of the factors. The neonatal sebaceous gland activity is obvious, the baby's sebum overflows, and the sebum overflows with the maternal androgen gradually disappears. Sebaceous gland activity gradually decreases with age until puberty, and begins to increase from 18 to 40 years old, until the symptoms of the elderly are alleviated, more men than women. In addition, mental factors, eating habits, alcohol and tobacco can stimulate the disease. The incidence of coronary heart disease, hypertension, heart failure, and B vitamin deficiency is higher, and AIDS patients can also see this disease.

an examination

Related inspection

Physical examination of skin diseases

Occurred in the face, also known as facial seborrheic dermatitis, facial seborrheic dermatitis often spread from the scalp, facial forehead, supraorbital, eyelids, nasolabial folds. At the beginning, the affected area is red, and the miliary size papules are formed. The color is reddish, and the color is reddish for a long time. The color is yellowish red, and the upper layer is greasy and thick. If the cream is like fat, or the water is yellow and sticky, itching is not only the eyebrows are often scratched. Rarely shed, there may be splits in the nasolabial folds and behind the ears.

Differential diagnosis

Differential diagnosis of red and cleft palate in the nasolabial fold:

1, head and face psoriasis

The damage is scattered into flakes, the boundary is clear, the scales are thick, the touch is uneven, the hair does not fall off, the short hair gathers into a bundle, and the heavy damage can be connected into a large piece, which spreads to the front hairline and invades the forehead several centimeters. Scratch the scales with a film phenomenon (ie, the scales are scraped off, under which is a red shiny film) and bleeding phenomenon (ie, the light scratch film can appear scattered at small bleeding points), film phenomenon and bleeding phenomenon is important for psoriasis damage feature.

2, rose pity

Occurs in the neck, torso, proximal extremities, oval-shaped rash, slightly yellow in the center, slightly elevated ridges, pale red, with white squama-like scales. From the beginning, it is a single lesion, called the mother spot; the mother spot is gradually larger, the diameter can reach 2~5cm or more, sometimes there are 2~3 mother spots at the same time, and after 1~2 months, small erythema appears successively. Occurred in the trunk, the long axis of the rash is consistent with the skin pattern, usually 4 to 6 weeks can self-resolve, no recurrence.

3, body

The damage edge is raised and narrow. The realm is clear, and there is a ring-shaped damage that the central healing expands to the surroundings. Itching is obvious, patients often have a history of hand and foot hyperthyroidism.

4, erythematous pemphigus

Mainly distributed in the face, neck, chest and back in the middle. Beginning on the face with symmetrical erythema, overlying scales and scarring, blister on the back of the neck and chest and back erythema, the formation of suede after rupture, Nie's sign positive. (ie, applying pressure on the blister top, you can see the blister infiltration into the surrounding epidermis; pulling the residual wall of the blister wall, causing further exfoliation of the surrounding epidermis; more importantly, the skin with normal appearance is also rubbed and broken).

5, slag-like dermatitis

Does not involve the scalp. Eyebrows and nasolabial folds are not good sites, and there are many medications for long-term external application of hormone preparations.

Occurred in the face, also known as facial seborrheic dermatitis, facial seborrheic dermatitis often spread from the scalp, facial forehead, supraorbital, eyelids, nasolabial folds. At the beginning, the affected area is red, and the miliary size papules are formed. The color is reddish, and the color is reddish for a long time. The color is yellowish red, and the upper layer is greasy and thick. If the cream is like fat, or the water is yellow and sticky, itching is not only the eyebrows are often scratched. Rarely shed, there may be splits in the nasolabial folds and behind the ears.

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