Lung diffusing dysfunction

Introduction The amount of dispersion depends on the partial pressure difference of the gas on the membrane, the area of dispersion, the distance, the time, the molecular weight of the gas and its solubility in the dispersion medium. Emphysema and other lung tissue lesions, diffuse pulmonary interstitial fibrosis and other diseases can cause a decrease in diffuse function. Clinically, when the pulmonary lesions produce diffuse dysfunction, there is often a significant ventilatory/blood flow imbalance, which results in hypoxia.

Cause

Emphysema and other lung tissue lesions, diffuse pulmonary interstitial fibrosis and other diseases. Chronic obstructive pulmonary disease, alveolar lesions, such as pulmonary infection, pulmonary edema, alveolar hemorrhage, alveolar proteinosis, thoracic and pleural lesions, cardiovascular disease, anemia or polycythemia patients, repeated upper respiratory tract infections, smoking History and long-term cough patients, patients with seasonal cough and asthma attacks.

an examination

Often there is a significant ventilatory/blood flow imbalance, which results in hypoxia.

(1) Diffusion function reduction can be seen in: 1 diffuse area reduction: such as emphysema, lobectomy, lung infection, pulmonary edema, pulmonary hemorrhage, pneumothorax, scoliosis and so on. 2 alveolar capillary membrane thickening: such as pulmonary interstitial fibrosis, sarcoidosis, asbestosis, scleroderma and so on. 3 hemoglobin oxygen carrying capacity decreased: such as anemia, carboxyhemoglobin.

(2) Increased diffuse function can be seen in polycythemia, intra-cardiac left to right shunt caused by increased pulmonary pressure.

Differential diagnosis

Pay attention to the identification of diffuse function drops caused by different diseases. Such as emphysema and other lung tissue lesions, diffuse pulmonary interstitial fibrosis and other diseases.

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